This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"It’s a feared moment for every scientist: the discovery that years of painstaking research has led to results that can't be repeated. Many think that poorly characterized antibodies have contributed to this reproducibility crisis more than any other laboratory tool. A new study published in Molecular Cell supports this hypothesis, at least in the context of chromatin immunoprecipitation. Although accurate ChIP interpretation depends on near-perfect antibody specificity, the report shows that many of these reagents are far less capable than their advertising suggests, which calls into question several widely accepted paradigms on genomic regulation. The study focused on histone post-translational modifications; specifically all three methylation states of lysine 4 on histone H3. Through ChIP experiments, H3K4 methylation has been strongly linked to transcriptional control..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
In this laboratory exercise students will have an opportunity to examine the …
In this laboratory exercise students will have an opportunity to examine the crystal structures, optical properties and health hazards of the common asbestos minerals. The laboratory will reinforce optical microscopic skills that students have learned in mineralogy and show them how mineralogy can be critical to understanding a current public policy issue.
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Overview: On this webpage you will find OER Chemistry textbooks along with …
Overview:
On this webpage you will find OER Chemistry textbooks along with supplemental materials and a few lecture videos. The purpose of these discipline-specific pages is to display content that might be of interest to faculty who are considering adopting open educational resources for use in their classes. This list of content is by no means exhaustive. The nature of open educational resources is very collaborative and it is in that spirit that we encourage any comments about the content featured on this page or recommendations of content that are not already listed here.
This module introduces balancing chemical reactions with stoichiometric coefficients. Includes a link …
This module introduces balancing chemical reactions with stoichiometric coefficients. Includes a link to an interactive website for practicing balancing reactions, a video showing specific practice problems, and a video with animations as visual aids demonstrating why we balance chemical reactions.
This assignment reviews basic of chemistry for students who should have had …
This assignment reviews basic of chemistry for students who should have had 2 introductory semesters of basic chemistry prior to enrolling in the Fundamental of Water Quality course for which the assignment is used. Assignment reviews basic equation balancing and questions about valence and concentration conversion that students will confront regularly in any geochemistry course.
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This course covers the following questions. What are the predominant heat producing …
This course covers the following questions. What are the predominant heat producing elements of the Earth? Where and how much are they? Are they present in the core of the Earth? Detection of antineutrinos generated in the Earth provides: 1) information on the sources of the terrestrial heat, 2) direct test of the Bulk Silicate Earth (BSE) model and 3) testing of non-conventional models of Earth's core. Use of antineutrinos to probe the deep interior of our planet is becoming practical due to recent fundamental advances in the antineutrino detectors.
In the master-equation formalism, a set of differential equations describe the time-evolution …
In the master-equation formalism, a set of differential equations describe the time-evolution of the probability distribution of an ensemble of systems. This can be used, for example, to describe the varied mRNA copy numbers found in individual cells in a population.
The stochastic simulation algorithm (SSA, Kinetic Monte Carlo, Gillespie algorithm) produces an …
The stochastic simulation algorithm (SSA, Kinetic Monte Carlo, Gillespie algorithm) produces an example trajectory for a particular member of a probabilistic ensemble by looping over the following steps. The current state of the system is used to determine the likelihood of each possible chemical reaction in relative comparison to the likelihoods for the other possible reactions, as well as to determine when the next reaction is expected. Pseudo-random numbers are drawn to "roll the dice" to determine exactly when the next reaction will proceed, and which kind of reaction it will happen to be.
This is an Excel spreadsheet and graph that illustrates standard "batch" and …
This is an Excel spreadsheet and graph that illustrates standard "batch" and Rayleigh decarbonation models and how they can be used to detect fluid infiltration during metamorphism of carbonates. It makes a good lecture demonstration, but with a few modifications can be turned into a laboratory exercise. Key variables are "hotlinked" directly into the batch and Rayleigh models so students can adjust them to get a feel for the influence of different model parameters. The included carbon isotope data are from marbles in the Jervois region, central Australia (Cartwright et al., 1997). Oxygen isotope data are also included in the spreadsheet.
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When 1,2-diketones ( α-diketones) on treatment with alcoholic KOH to give alpha- …
When 1,2-diketones ( α-diketones) on treatment with alcoholic KOH to give alpha- hydroxy acid. This is intramolecular base catalyased reaction. This is called as pi molecular rearrangement with second order rate reaction. In this rearrangement migrating group migrates towards electron deficient carbon atom.In this rearrangement Less eletron releasing group migrates first.
In this activity students work through a binary eutectic phase diagram in …
In this activity students work through a binary eutectic phase diagram in small groups and try to determine a set of generalizations that explain the behavior of such systems (e.g., "the first liquid produced upon heating is always the eutectic composition").
(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)
We are happy to welcome you to our second Open Educational Resource …
We are happy to welcome you to our second Open Educational Resource (OER) textbook, Biochemistry Free For All. Biochemistry is a relatively young science, but its rate of growth has been truly impressive. The rapid pace of discoveries, which shows no sign of slowing, is reflected in the steady increase in the size of biochemistry textbooks. Growing faster than the size of biochemistry books have been the skyrocketing costs of higher education and the even faster rising costs of college textbooks. These unfortunate realities have created a situation where the costs of going to college are beyond the means of increasing numbers of students.
Chemical Biology research uses the tools of chemistry and synthesis to understand …
Chemical Biology research uses the tools of chemistry and synthesis to understand biology and disease pathways at the molecular level. Advanced Biological Chemistry interests include diverse topics such as nucleic acids, DNA repair, bioconjugate chemistry, peptides and peptidomimetics, glycoscience, biomolecular structure and function, imaging, and biological catalysis. Biophysical Chemistry represents the union of Chemistry, Physics, and Biology using a variety of experimental and theoretical approaches to understand the structure and function of biological systems.
A free online textbook for biophysical chemistry. The book covers probability, statistics, …
A free online textbook for biophysical chemistry. The book covers probability, statistics, thermodynamics, kinetics, Monte Carlo methods, biochemistry, diffusion, stochastic processes, and others.
CHE106 - Chemical Science Concepts An introductory elective course for non-science majors. The …
CHE106 - Chemical Science Concepts An introductory elective course for non-science majors. The concepts of general chemistry, organic chemistry and biochemistry are presented through a forensic science approach.Mercer County Community CollegeDr. Lisa Meseroll, PhD
Course Goals and Learning Objectives. The goal of this course is to …
Course Goals and Learning Objectives. The goal of this course is to give the student a basic understanding of chemistry and physical processes in the context of food chemistry, metabolism and cooking. The course also necessarily makes connections to the future sustainability of food and water. We aim to prepare the student for the increasingly urgent and complex national dialogue on the interrelated topics of global climate change, energy, pollution, extinction and the food supply. The specific objectives of this course are to provide the student with the basic vocabulary of chemistry, and a basic understanding of the experimental process as it relates to food chemistry and cooking.
This illustration gives you the detailed information on classification of chromatographic methods. Chromatographic …
This illustration gives you the detailed information on classification of chromatographic methods. Chromatographic methods had 3 main types that is based on stationary, stationary phase format & mobile phase.
Sequence of laboratory activities to develop familiarity with geochemistry bench laboratory experimental …
Sequence of laboratory activities to develop familiarity with geochemistry bench laboratory experimental methods; demonstration of different weathering rates of different Ca-bearing minerals; connection between minerals present in a system and nutrient (Ca) availability
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This exercise uses a number of Excel spreadsheets to calculate mineral formulae …
This exercise uses a number of Excel spreadsheets to calculate mineral formulae from compositional (microprobe) data. Numerous computational models are presented for most mineral groups (e.g. amphiboles, pyroxenes, micas), and students must critically evaluate which of these models is most applicable. Stoichiometry and charge balance are used to determine ferric/ferrous ratios--which is important for further applications such as geothermobarometry. Students are also asked directed questions about: compositional variation of the rock-forming mineral groups; representative complete, limited, and coupled solid solutions; site occupancy of major elements, as determined by the various computational models used; graphical representation of the calculated mineral formulae; and the composition and significance of certain varieties of these rock-forming minerals are addressed.
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This is a spreadsheet that I use in petrology to walk students …
This is a spreadsheet that I use in petrology to walk students through calculating Rb-Sr isochrons and talking about isotope heterogeneity and sampling at various scales. The example exercise is the Tuolumne intrusive series. The file, available for download below, contains workbooks (see different tabs) with example isochrons and a spreadsheet of data for the homework problems.
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