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  • The Human Genome
The Human Genome Project - The Use of Genetic Screening Technology
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This unit includes one week of lessons which immediately follow the Genetics and DNA units. The previous knowledge gained from these units, as well as a previous project where students researched and shared with their classmates a specific genetic disorder, will provide the background for students to participate in a debate about the ethical issues of applying information available through the Human Genome Project (HGP).

Subject:
Life Science
Material Type:
Reading
Unit of Study
Author:
Ethel Gaides
Emelia Fleck
Beverly Tedeschi
Date Added:
10/28/2017
Language & Life Sciences: Mapping the Human Genome
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Public Domain
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Rather than focus on the scientific details of this discovery, this chapter gives an overview of the important concepts related to DNA's initial discovery and later research conducted in this field. Teachers can use the lesson plans and materials to help students understand these fundamental concepts and gain a command of the vocabulary necessary to discuss them. Given the amazing advances in biological research and the new knowledge that has become available to human beings about their own biological makeup, it is important for students to know basic concepts related to DNA research and the human genome project. This following lesson provides a basic introduction to this topic in an interactive fashion.

Subject:
Language Education (ESL)
Biology
Material Type:
Lesson Plan
Teaching/Learning Strategy
Provider:
U.S. Department of State, Bureau of Educational and Cultural Affairs
Provider Set:
U.S. Department of State Bureau of Educational and Cultural Affairs
Author:
Donna M. Brinton, Christine Holten, Jodi L. Nooyen
Date Added:
06/12/2012
Genetic Disorders
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DNA is the key to human life. When DNA is corrupted, changes occur in specific parts of the organism. Some of these changes can be fatal while others are beneficial. In this lesson we will look at the process of DNA mutation and how it impacts proteins produced by the organism.  You will research different genetic disorders and empathize with the impacts they have on your body.StandardsBIO.B.2.1 Compare Mendelian and non-Mendelian patterns of inheritance.

Subject:
Life Science
Biology
Material Type:
Lesson Plan
Author:
Bonnie Waltz
Tracy Rains
Deanna Mayers
Date Added:
10/08/2017
Human Genome Project
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This video segment from NOVA: "Cracking the Code of Life" looks at the meaning and significance of the effort to decode the human genome.

Subject:
Engineering
Life Science
Material Type:
Activity/Lab
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Teachers' Domain
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
09/26/2003
Human Genome Project
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The human genome project was one the most important human discoveries in the past 100 years. It creates a map of every gene in the human body.  Through this lesson you will explore the history of the genome project, its applications today, and implications for your life.  In addition, you will reflect on its impact on your life and determine if you think this is a positive or negative change. Based on your understanding, you will look at different perspectives with empathy to better understand how this technology impacts other people's lives.StandardsBIO.B.2.4Explain how genetic engineering has impacted the fields of medicine, forensics, and agriculture (e.g., selective breeding, gene splicing, cloning, genetically modified organisms, gene therapy).

Subject:
Life Science
Biology
Material Type:
Lesson Plan
Author:
Bonnie Waltz
Tracy Rains
Deanna Mayers
Date Added:
10/08/2017
Bioinformatics
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This exercise contains two interrelated modules that introduce students to modern biological techniques in the area of Bioinformatics, which is the application of computer technology to the management of biological information. The need for Bioinformatics has arisen from the recent explosion of publicly available genomic information, such as that resulting from the Human Genome Project.

Subject:
Biology
Material Type:
Activity/Lab
Data Set
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Teaching With Data
Author:
Monica Bruckner
Date Added:
08/28/2012
The Science Scoop: The Human Genome Project
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This fun Web site is part of OLogy, where kids can collect virtual trading cards and create projects with them. Here, they learn about the human genome project by clicking through an online slide show, hosted by kids, that answers these questions: What's a genome, anyway? What is the human genome project? What does it mean to me?

Subject:
Life Science
Genetics
Material Type:
Data Set
Provider:
American Museum of Natural History
Provider Set:
American Museum of Natural History
Date Added:
10/15/2014
Using DNA to Identify People
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it would be ideal if students already have learned that DNA is the genetic material, and that DNA is made up of As, Ts, Gs, and Cs. It also would help if students already know that each human has two versions of every piece of DNA in their genome, one from mom and one from dad. The lesson will take about one class period, with roughly 30 minutes of footage and 30 minutes of activities.

Subject:
Criminal Justice
Biology
Genetics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Megan E. Rokop
Date Added:
05/14/2015
Frontiers of Knowledge: Genomic Advances on a Grand Scale
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For more than two decades J. Craig Venter and his research teams have been pioneers in genomic research. Regarded as one of the leading scientist of the 21st century, Venter discusses how he is applying tools and techniques developed to sequence the human genomes to discover new genes of microbes from around the world. (57 minutes)

Subject:
Biology
Genetics
Material Type:
Lecture
Provider:
U.C. San Diego
UCTV Teacher's Pet
Date Added:
05/08/2011
Learning about Genetic Disorders
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This activity provides brief instructions and recommended reliable sources for students to investigate and report on a genetic disorder of their choice.

Subject:
Life Science
Genetics
Material Type:
Activity/Lab
Provider:
Serendip Studio
Provider Set:
Minds-On Activities for Teaching Biology
Author:
Ingrid Waldron
Date Added:
11/05/2014
Language & Life Sciences: Controversial Issues in Gene Research
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One of the fastest-growing areas of medical research is that of genetic testing and gene therapy. This chapter introduces students to this area of DNA research and helps them explore the related ethical issues. Scientists have recently completed a preliminary ‰ŰĎmap‰Ű of all the genes in the human body. This is also known as the Human Genome Project and consists of all the sequences of DNA chemical units that tell a cell how to behave. This accomplishment has incredible benefits. However, it also raises new, complex issues that society cannot ignore.

Subject:
Language Education (ESL)
Material Type:
Lesson Plan
Teaching/Learning Strategy
Provider:
U.S. Department of State, Bureau of Educational and Cultural Affairs
Provider Set:
U.S. Department of State Bureau of Educational and Cultural Affairs
Author:
Donna M. Brinton, Christine Holten, Jodi L. Nooyen
Date Added:
06/12/2012
Genetic Origins
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The goal of the Genetic Origins Program is to allow students to use their own DNA variations (polymorphisms) as a means to explore our shared genetic heritage and its implications for human health and society. Genetic Origins focuses on two types of DNA variations: an Alu insertion polymorphism on chromosome 16 (PV92) and single nucleotide polymorphisms (SNPs) in the control region of the mitochondrial (mt) chromosome. With two alleles and three genotypes, PV92 is a simple genetic system that illustrates Mendelian inheritance on a molecular level. PV92 data is readily analyzed using population statistics. The mt control region is one of the simplest regions of human DNA to sequence. With a high mutation rate, the mt control region is the "classical" system for studying human and primate evolution. The Genetic Origins site and linked Bioservers site have all the information needed for students to perform the Alu and mt DNA experiments and analyze the results - including online protocols, reagents, animations and videos explaining key concepts, and database tools.

Subject:
Genetics
Material Type:
Activity/Lab
Simulation
Provider:
Cold Spring Harbor Laboratory
Provider Set:
Dolan DNA Learning Center
Date Added:
02/16/2011
Language & Life Sciences: Drugs of the Future
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Public Domain
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New understanding of human genetics will not only make it easier to diagnose diseases, it will also change how diseases are treated. Scientists and drug companies are using knowledge from the Human Genome Project to find cures for everything from cancer to obesity (see chapter 1: Mapping the Human Genome). This new medicine is called "genomic" medicine. Medicine is changing at a rapid rate as a result of the new knowledge of the human genome. It is important for students to know how drugs and treatments are changing and will continue to change.

Material Type:
Lesson Plan
Teaching/Learning Strategy
Provider:
U.S. Department of State, Bureau of Educational and Cultural Affairs
Provider Set:
U.S. Department of State Bureau of Educational and Cultural Affairs
Author:
Donna M. Brinton, Christine Holten, Jodi L. Nooyen
Date Added:
06/12/2012
Retinitis pigmentosa: Genetic Eye Disease
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By examining the progress of a genetic eye disease, students learn about eyes, genetic disorders, and neurons in this case designed for clickers and large lecture sections.

Subject:
Life Science
Material Type:
Activity/Lab
Assessment
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Teaching and Learning Economics (SERC)
Author:
Eric Ribbens
Date Added:
08/28/2012
What Is the Genome Made Of?
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Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated; and it carries a store of vital information that is used in the cell to produce proteins. The first two properties of DNA are analysed in this unit.

Subject:
Genetics
Material Type:
Activity/Lab
Reading
Syllabus
Provider:
The Open University
Provider Set:
Open University OpenLearn
Date Added:
09/06/2007
Engineering Nature: DNA Visualization and Manipulation
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Students are introduced to genetic techniques such as DNA electrophoresis and imaging technologies used for molecular and DNA structure visualization. In the field of molecular biology and genetics, biomedical engineering plays an increasing role in the development of new medical treatments and discoveries. Engineering applications of nanotechnology such as lab-on-a-chip and deoxyribonucleic acid (DNA) microarrays are used to study the human genome and decode the complex interactions involved in genetic processes.

Subject:
Engineering
Life Science
Genetics
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Genome Facts
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This list from NOVA: "Cracking the Code of Life" Web site provides some of the basic, yet impressive, facts and figures about the Human Genome Project.

Subject:
Life Science
Material Type:
Activity/Lab
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Teachers' Domain
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
09/26/2003
Classifying Animals by Appearance Versus DNA Sequence
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The topic of this video module is how to classify animals based on how closely related they are. The main learning objective is that students will learn how to make phylogenetic trees based on both physical characteristics and on DNA sequence. Students will also learn why the objective and quantitative nature of DNA sequencing is preferable when it come to classifying animals based on how closely related they are. Knowledge prerequisites to this lesson include that students have some understanding of what DNA is and that they have a familiarity with the base-pairing rules and with writing a DNA sequence.

Subject:
Biology
Genetics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Megan E. Rokop
Date Added:
06/11/2012
Interdisciplinary Integrated Unit on Dna and Genetics Part A: Science
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Part of an interdisciplinary week-long unit on DNA and genetics with activities in science, math, and language arts. This lesson is Part A: Science. Students complete a teacher-made scavenger hunt as an introduction to DNA and genetics, then watch a short video and use their science books to learn more about the topic. Students work in pairs to investigate DNA, genetics, and cloning through internet research and compile their information in the form of their own internet scavenger hunt.

Subject:
Biology
Genetics
Material Type:
Lesson Plan
Provider:
University of North Carolina at Chapel Hill School of Education
Provider Set:
LEARN NC Lesson Plans
Author:
Jane Lentz
Jimmy White
Marlene Smith
Tori Goldrick
Date Added:
10/12/2006
You Can’t Always Get What You Want: A Lesson in Human Evolution
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This lesson introduces students to the concepts of evolution, specifically the evolution of humans. So often our students assume that humans are well adapted to our environments because we are in control of our evolutionary destiny. The goal is to change these types of misconceptions and get our students to link the concepts learned in their DNA, protein synthesis, and genetics units to their understanding of evolution. Students will also discover that humans are still evolving and learn about the traits that are more recent adaptations to our environment. The lesson is designed to take two one-hour class periods to complete. The activities will allow students to draw connections between environmental pressures and selected traits, both through data analysis and modeling. Most activities can be done without any special materials, although the Modeling Natural Selection activity needs either a tri-colored pasta, or tricolored beans, to be completed effectively.

Subject:
Life Science
Genetics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Julie Boehm
Date Added:
02/12/2015
Translational Bioinformatics
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'Translational Bioinformatics' is a collection of articles which reads as a "book" to be used as a reference or tutorial for a graduate level introductory course on the science of translational bioinformatics. Translational bioinformatics is an emerging field that addresses the current challenges of integrating increasingly voluminous amounts of molecular and clinical data. Its aim is to provide a better understanding of the molecular basis of disease, which in turn will inform clinical practice and ultimately improve human health. The concept of a translational bioinformatics introductory book was originally conceived in 2009 by Jake Chen and Maricel Kann. Each chapter was crafted by leading experts who provide a solid introduction to the topics covered, complete with training exercises and answers. The rapid evolution of this field is expected to lead to updates and new chapters that will be incorporated into this collection.

Subject:
Health, Medicine and Nursing
Information Science
Material Type:
Data Set
Primary Source
Provider:
Public Library of Science
Provider Set:
Computer & Information Sciences
Date Added:
04/11/2016
Language & Life Sciences: eJournals
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Biotechnology is perhaps the most rapidly advancing area in science today. The Advances in Biotechnology volume has been created to provide language teachers with resources about breakthroughs in biotechnology. Each chapter of the volume highlights one aspect of research in the field of DNA and genetics along with its applications to and implications for society. The chapters feature relevant background information on each topic, interactive and communicative classroom activities, and a list of related print and Internet resources that will allow teachers to expand the lesson further.

Subject:
Language Education (ESL)
Genetics
Material Type:
Activity/Lab
Lesson Plan
Reading
Teaching/Learning Strategy
Provider:
U.S. Department of State, Bureau of Educational and Cultural Affairs
Provider Set:
U.S. Department of State Bureau of Educational and Cultural Affairs
Author:
Donna M. Brinton, Christine Holten, Jodi L. Nooyen
Date Added:
06/12/2012
Human Biology - Genetics (Student's Edition)
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The Genetics Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Subject:
Biology
Genetics
Material Type:
Activity/Lab
Textbook
Provider:
CK-12 Foundation
Provider Set:
CK-12 FlexBook
Author:
Program in Human Biology, Stanford University
Date Added:
02/04/2011
DNA Build
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
Evolution Connection: DNA Replication
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This short slide set explains the fidelity of DNA replication in evolutionary terms. Save the slide set to your computer to view the explanation and notes that go along with each slide.

Subject:
Biology
Genetics
Material Type:
Diagram/Illustration
Lecture Notes
Teaching/Learning Strategy
Provider:
National Center For Science Education
University of California Museum of Paleontology
Provider Set:
Understanding Evolution
Date Added:
05/17/2013
Bacteria Transformation
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Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014
Biology, Genetics, DNA Structure and Function, DNA Structure and Sequencing
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By the end of this section, you will be able to:Describe the structure of DNAExplain the Sanger method of DNA sequencingDiscuss the similarities and differences between eukaryotic and prokaryotic DNA

Subject:
Applied Science
Life Science
Biology
Material Type:
Module
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
07/10/2017
Genetic Variation
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This video segment from NOVA: "Cracking the Code of Life" explores the genetic similarities and differences among organisms.

Subject:
Life Science
Material Type:
Activity/Lab
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Teachers' Domain
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
09/26/2003
Evolution: What Makes us Human?
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TED Studies, created in collaboration with Wiley, are curated video collections — supplemented by rich educational materials — for students, educators and self-guided learners. in What Makes Us Human?, TED speakers tackle humanity’s oldest and deepest questions by playing with primates, excavating ancient remains, and DNA-mapping family trees. Explore how the next chapters of our own evolutionary story will be written thanks to new technologies that trace our origin. 

Subject:
Life Science
Material Type:
Lecture
Reading
Teaching/Learning Strategy
Provider:
TED
Provider Set:
TED Studies
Author:
James Calcagno
Date Added:
01/06/2017
Biology, Genetics, Biotechnology and Genomics, Biotechnology
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By the end of this section, you will be able to:Describe gel electrophoresisExplain molecular and reproductive cloningDescribe uses of biotechnology in medicine and agriculture

Subject:
Applied Science
Life Science
Biology
Material Type:
Module
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
07/10/2017
Introduction to Genetic Engineering and Its Applications
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Students learn how engineers apply their understanding of DNA to manipulate specific genes to produce desired traits, and how engineers have used this practice to address current problems facing humanity. They learn what genetic engineering means and examples of its applications, as well as moral and ethical problems related to its implementation. Students fill out a flow chart to list the methods to modify genes to create GMOs and example applications of bacteria, plant and animal GMOs.

Subject:
Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014
Teaching Molecular Evolution and Phylogenetics
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This activity uses DNA sequences, protein sequence, and chromosome-density maps to re-trace the ancestry of humans and some of their closest relatives.

Subject:
Life Science
Genetics
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Nathan Lents
Date Added:
11/06/2014
Unit 4: Genomics
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Anchoring Phenomenon: Identical twins have the same DNA yet one was diagnosed with breast cancer and the other was not?? One about diabetes? Unit Essential Question: Why are some people diagnosed with diabetes and breast cancer while others are not?

Subject:
Biology
Material Type:
Unit of Study
Provider:
Portland Metro STEM Partnership
Provider Set:
Patterns Biology
Date Added:
08/03/2018
Biology, Genetics, DNA Structure and Function, Historical Basis of Modern Understanding
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By the end of this section, you will be able to:Explain transformation of DNADescribe the key experiments that helped identify that DNA is the genetic materialState and explain Chargaff’s rules

Subject:
Applied Science
Life Science
Biology
Material Type:
Module
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
07/10/2017