This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Antibiotic-resistant bacteria like carbapenem-resistant Enterobacteriaceae (CRE) pose a serious threat to human health. Some resistant pathogens can exist alongside our commensal microbiota at undetectable levels. Antibiotic use can lead to outgrowth of these subclinically colonized bacteria. A recent study sought to better understand the interaction between the gut microbiota and CRE during subclinical colonization and outgrowth. First, researchers exposed wild-type mice to the CRE _K. pneumoniae_. While the levels of _K. pneumoniae_ were not detectable after exposure, the post-exposure microbiome was disrupted. Then, administration of an antibiotic cocktail, ampicillin, vancomycin, or azithromycin induced _K. pneumoniae_ outgrowth while reducing overall microbial diversity. Vancomycin only induced outgrowth in a subset of mice. The researchers found these outgrowth-susceptible mice had differences in mRNA stability pathways and xylose abundance..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Like most animals, mosquitoes carry many microbes in and on their bodies. These microbial communities (microbiota) impact the mosquitoes’ growth, survival, reproduction, and capacity to transmit pathogens, but the tools available to researchers to study mosquito microbiotas are limited. In other species, particularly mammals, microbiota transfer is a useful method to research microbial dynamics. However, such transfers had not previously been attempted in mosquitoes, until a recent study where researchers successfully transferred microbiota between individual _Aedes aegypti_ mosquitoes. as well as between _Culex quinquefasciatus_ and _A. aegypti_ mosquitoes. They transferred whole-body microbiota from adult donors to larvae and then observed the microbiota dynamics. The recipient mosquitoes retained most of the donor bacterial groups, suggesting that the transfer was successful, and the typical microbiota shifts occurred as the mosquitoes moved from larval stages to adulthood..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.