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Diabetes - A Global Challenge - Clinical Manifestation of Diabetes and Treatment Part 1 (25:27)
Rating

The aim of this presentation is to address different hot topics in our current understanding of aetiology as well as of the pathophysiology of Type 2 Diabetes. We’ll address how genetic as well as epi-genetic and non-genetic mechanisms may be involved in the complex mechanisms underlying type 2 diabetes. We’ll also introduce recent data suggesting that immature stem-cell functions are likely to play an important role for development of type 2 diabetes and its associated cardiometabolic disturbances. Finally we’ll address the current treatment options of disease with respect of both pharmacological and non-pharmacological treatment modalities.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Allan Vaag
Date Added:
01/07/2014
Diabetes - A Global Challenge - Clinical Manifestation of Diabetes and Treatment Part 2 (11:32)
Rating

This presentation address the multifactorial etiology of type 2 diabetes. The multifactorial etiology, can be divided into three major categories, primary predisposing factors, secondary precipitating factors, as well as tertiary accelerating factors.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Allan Vaag
Date Added:
01/07/2014
Diabetes - A Global Challenge - Clinical Manifestation of Diabetes and Treatment Part 3 (22:44)
Rating

The aim of this presentation is to address and understand the paradigm shifting consequences of the Thrifty Phenotype Hypothesis as a conceptual framework to understand the roots of type 2 diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Allan Vaag
Date Added:
01/07/2014
Diabetes - A Global Challenge - Diabetes Theraphy - Incretins and Surgery Part 1 (07:45)
Rating

During the last couple of decades two new remarkably successful principles for diabetes therapy have appeared and are now used worldwide. These are incretin based therapy and surgical therapy. These two are at some extent linked together and in this lecture we’ll provide an introduction to these two principles for diabetes therapy.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Jens Juul Holst
Date Added:
01/07/2015
Diabetes - A Global Challenge - Diabetes Theraphy - Incretins and Surgery Part 2 (09:49)
Rating

In this presentation we’ll talk about the effects of GLP-1 (Glucagon Like Peptide 1), GLP-1 has important actions on gastrointestinal secretion and motility, and it acts to inhibit appetite and food intake. In continuation of the effects of GLP-1, we’ll talk about GLP-1, GIP, lipids, proteins, and dipeptidyl peptidase-4.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Jens Juul Holst
Date Added:
01/07/2015
Diabetes - A Global Challenge - Diabetes Theraphy - Incretins and Surgery Part 3 (18:56)
Rating

This presentation talks about intravenously GLP-1 infusion to patients with type 2 diabetes. The GLP-1 infusion is capable of restoring fasting glucose concentrations during the night time and can nearly normalize the meal-induced glucose excursions after meal ingestion. GLP-1 has many attractive actions regarding diabetes type 2 treatment, which is the theme of this presentation.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Jens Juul Holst
Date Added:
01/07/2015
Diabetes - A Global Challenge - Epidemiology of Diabetes Part 1 (07:57)
Rating

This presentation provides an introduction to some of the basic aspects of the epidemiology of diabetes. In continuation of this we’ll discuss why diabetes is such a serious disease and what the biological mechanics of the disease are.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Thorkild I. A. Sørensen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Epidemiology of Diabetes Part 2 (12:21)
Rating

This presentation will look at how the distribution of diabetes is, thus we’ll discuss how the distribution of diabetes are by type, gender, age, geographical region and ethnicity. The purpose of this discussion is to understand how serious a health problem the global epidemic of diabetes is, while increasing the understanding that it’s extremely necessary that we do whatever we can to fight against the diabetes epidemic in the future.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Thorkild I. A. Sørensen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Epidemiology of Diabetes Part 3 (05:50)
Rating

This presentation tries to identify the most important risk factors for developing diabetes. In order to take the next steps in planning diabetes prevention, we need to know what distinguished those at risk of developing diabetes from those who aren’t or are at lower risk within the populations.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Thorkild I. A. Sørensen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Genetic Aspects of Non-autoimmune Diabetes Part 1 (06:40)
Rating

This presentation provides an introduction to the genetic aspects of non-autoimmune diabetes. First we’ll introduce the genetic basis of diabetes, then we’ll talk about methods to identify genetic loci associated with diabetes and pre-diabetic traits. In continuation of this, we’ll provide examples of monogenic forms of diabetes and finally we’ll discuss common forms of non-autoimmune diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Torben Hansen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Genetic Aspects of Non-autoimmune Diabetes Part 2 (08:10)
Rating

This presentation provides an introduction to methods used to identify genetic loci affecting diabetes and pre-diabetes traits. Furthermore we’ll discuss aspects that are important when choosing and considering different methods.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Torben Hansen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Genetic Aspects of Non-autoimmune Diabetes Part 3 (20:58)
Rating

In this presentation we’ll present a genetic atlas of the non-autoimmune diabetes and describe monogenic forms of diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Torben Hansen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Genetic Aspects of Non-autoimmune Diabetes Part 4 (20:39)
Rating

This presentation provides an introduction to the genetics behind the common forms of type 2 diabetes. Furthermore we’ll provide an introduction to the Genome-Wide Association Study, this study is a hypothesis generating method that contains a discovery and a replication sample.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Torben Hansen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Inflammatory Beta-cell Destruction in Diabetes Part 1 (08:34)
Rating

This presentations discuss diabetes as an disease of the pancreatic beta cell, in continuation of this, we’ll discuss what causes beta cell failure in type 1 and type 2 diabetes. Furthermore we’ll discuss the innate immune system and the beta cell failure, and inflammatory mediators as therapeutic targets of type 1 and type 2 diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Thomas Mandrup-Poulsen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Inflammatory Beta-cell Destruction in Diabetes Part 2 (18:04)
Rating

This presentation provides an introduction to the immune system and how it’s activated. In continuation of this we’ll discuss how inflammatory beta cell destruction comes about in type 1 diabetes. Furthermore we’ll discuss how beta cell failure occur in type 2 diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Thomas Mandrup-Poulsen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Interview with Dr. Robert Ross - on Physical Activity and Weight Management (09:57)
Rating

In this interview with Dr. Robert Ross we discuss what a successful obesity management is and what a clinical meaningful weight loss is? Furthermore we discuss recommendations regarding physical activity for health in the general population and which strategies we should take to have people sustain physical activity in the long run.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Dr. Robert Ross
Professor Bente Stallknecht
Date Added:
01/07/2014
Diabetes - A Global Challenge - Muscle as an Endocrine Organ - Role in Diabetes (13:08)
Rating

The aim of this lecture is to give the student a new perspective on the muscle, the largest organ in the body. Skeletal muscles are primary identified by the mechanical activity required for posture, movement and breathing, which depends on muscle fiber contractions. However skeletal muscle isn’t just a component in our locomotor system.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Bente Klarlund Pedersen
Date Added:
01/07/2016
Diabetes - A Global Challenge - Novel Approaches in Drug Development Part 1 (11:09)
Rating

This presentation focuses on the current and novel approaches used to develop drugs in the treatment of obesity. We’ll introduce the student to the physiological regulation of appetite and satiety in relation to meals, then we’ll provide an short overview of the previous and current treatment on the market for the treatment of obesity and finally we’ll describe some of the promising novel approaches pursued for future treatment.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Birgitte Holst
Date Added:
01/07/2015
Diabetes - A Global Challenge - Novel Approaches in Drug Development Part 2 (13:10)
Rating

This presentation provides an overview of the existing treatment available for treatment of obesity. Genetic studies have revealed that the genes contributing to development of obesity is mainly located in the brain, therefore it would be logical to tro to target the brain when pursuing drugs for the treatment of obesity. However it’s not that simple.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Birgitte Holst
Date Added:
01/07/2015
Diabetes - A Global Challenge - Physical Activity and its Influence on Obesity, Insulin Resistance and Diabetes Part 1 (13:13)
Rating

This presentation focus’ on the health benefits of being physically active and describes how physical training affects energy balance and metabolic health. Furthermore we’ll discuss the potential of physical training in prevention and treatment of obesity and diabetes and finally we’ll demonstrate methods that can be used to evaluate physical fitness, body fat distribution and insulin sensitivity.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Bente Stallknecht
Date Added:
01/07/2014
Diabetes - A Global Challenge - Physical Activity and its Influence on Obesity, Insulin Resistance and Diabetes Part 2 (22:16)
Rating

This presentation provides an introduction to physical activity and its influence on obesity, insulin resistance and diabetes type 2. Furthermore we’ll talk about how we can measure body fat distribution, insulin sensitivity and insulin resistance.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Bente Stallknecht
Date Added:
01/07/2014
Diabetes - A Global Challenge - Physical Activity and its Influence on Obesity, Insulin Resistance and Diabetes Part 3 (15:51)
Rating

This presentation talks about how it’s important to propagate the message that physical exercise has other health benefits effect than weight reduction and even if the body weight isn’t reduced by physical exercise, the body composition might change. Furthermore we’ll talk about the metabolic syndrome.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Bente Stallknecht
Date Added:
01/07/2014
Diabetes - A Global Challenge - Physical Inactivity - A Major Risk Factor for Diabetes (16:46)
Rating

This presentation aims to increase the students knowledge of physical inactivity and how it’s a major risk factor for developing diabetes, independent of body weight. Moreover we’ll discuss how we fight the global burden of a physical inactive lifestyle.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Bente Klarlund Pedersen
Date Added:
01/07/2016
Diabetes - A Global Challenge - Physiological Regulation of Blood Glucose Part 1 (25:57)
Rating

This presentation talks about glucose regulation, how it’s possible to maintain a constant glucose level and physical regulation of plasma glucose. In continuation of this we’ll talk about diabetic complication, like neuropathy, retinopathy, nephropathy, chronic hyperglycemia, which can lead to myocardial infarction, stroke and amputations.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Jens Juul Holst
Date Added:
01/07/2014
Diabetes - A Global Challenge - Physiological Regulation of Blood Glucose Part 2 (16:52)
Rating

This presentation provides an introduction to the islet hormones effects on various target tissues. Insulin is such a hormone, and in continuation of this, we’ll talk about the insulin receptor signaling. Furthermore we’ll talk about liver cells, fat cells, Lipogenesis, Insulin dose-response curves, C-peptide, Glucagon and glucagon producing tumor.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Jens Juul Holst
Date Added:
01/07/2014
Diabetes - A Global Challenge - Physiological Regulation of Blood Glucose Part 3 (09:47)
Rating

This presentation focus' on glucose and insulin, and how these are integrated in the intact organism, in continuation of this we’ll talk about, insulin and glucagon secretion, hepatic glucose production and plasma glucose concentrations. The purpose of this is to get an understanding of what happens in the body when you have type 2 diabetes. Furthermore we’ll talk about the possibility of developing an glucagon receptor antagonist, regarding the therapy of diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Jens Juul Holst
Date Added:
01/07/2014
Diabetes - A Global Challenge - Stem Cell Based Therapy of Diabetes Part 1 (13:24)
Rating

This presentation provides an introduction to diabetes (Type 1 and Type 2) development and how it’s a significant global burden. We’ll also discusses how stem cell based therapy can be used to treat diabetes and which advantages and disadvantages this treatments provides.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Ole Dragsbæk Madsen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Stem Cell Based Therapy of Diabetes Part 2 (09:29)
Rating

This presentation provides an introduction to The Edmonton Protocol, which was published back in year 2000 from University of Edmonton. In continuation of this, we’ll talk about insulin injections and hypoglycemia.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Ole Dragsbæk Madsen
Date Added:
01/07/2014
Diabetes - A Global Challenge - Stem Cell Based Therapy of Diabetes Part 3 (25:32)
Rating

This presentation discusses the possibility of finding a cure for type 1 diabetes, and hereby developing a product, that maintains a normal blood glucose level without insulin treatment. In continuation of this, we’ll provide an introduction to beta cell replacement therapy based on The Edmonton Protocol, however we’ll be focusing on relying on stem cell technology rather than that of organ donor islets. Furthermore we’ll discuss how we can combine an encapsulation strategy, so we can avoid the use of immuno-suppression.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Ole Dragsbæk Madsen
Date Added:
01/07/2014
Diabetes - A Global Challenge - The Relation Between Obesity and Diabetes (15:06)
Rating

In this presentation we’ll take a closer look at the relation between obesity and diabetes. Although it may seem simple, there are various aspects that make the relation between obesity and diabetes, more complex than at first sight.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Thorkild Sørensen
Date Added:
01/07/2014
Diabetes - A Global Challenge - The Role of Inflammation in Type 2 Diabetes (14:12)
Rating

In this lecture we’ll discuss the role of inflammation in type 2 diabetes. In patients with type 2 diabetes, cardiovascular complications are of particular interest, as these are mainly responsible for the increase of mortality and obesity in diabetic patients compared with healthy subjects. In continuation of this and in order to understand why diabetes is an inflammatory disease, we’ll provide an introduction to the acute phase response.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Bente Klarlund Pedersen
Date Added:
01/07/2016
Diabetes - A Global Challenge - Translational Metabolism Part 1 (12:56)
Rating

In this presentation we’ll translate our knowledge from genetics into clinically relevant patient stories. We’ll present case stories of translational metabolism, which means that we go from genotype to phenotype. Translational science is a multidisciplinary form of science that bridges the gap between basic science and applied science.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Assistant Professor Signe Torekov
Date Added:
01/07/2015
Diabetes - A Global Challenge - Translational Metabolism Part 2 (07:10)
Rating

In this presentation aim to increase the student’s knowledge about translational metabolism, in continuation of this we’ll elaborate on topics related to food ingestion, bone resorption, the intestinale hormone GIP, genetic variation in the receptor of GIP in relation to fracture risk, food availability and bone regulation, blood glucose and future treatment of osteoporosis.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Associate Professor Signe Sørensen Torekov
Date Added:
01/07/2015
Diabetes - A Global Challenge - Treatment of Hyperglycaemia with T2D Patients Part 1 (14:15)
Rating

This presentation discuss how to treat hyperglycaemia in patients with type 2 diabetes. The cornerstone in the treatment is weight loss and increased physical activity, but most patients need pharmacological treatment from the time of diagnosis in order to control hyperglycemia. Furthermore we’ll discuss the use of all diabetic agents in patient with type 2 diabetes and how it’s important that the anti diabetic treatment is individualized.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Sten Madsbad
Date Added:
01/07/2015
Diabetes - A Global Challenge - Treatment of Hyperglycaemia with T2D Patients Part 2 (08:25)
Rating

This presentation discuss the new antidiabetic agents. We have the incretin based therapy which include two groups of drugs, DDP-4 inhibitors and GLP-1 receptor agonist. Furthermore we’ll provide an introduction to the hormones GLP-1 and GIP and their effect on insulin.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Sten Madsbad
Date Added:
01/07/2015
Diabetes - A Global Challenge - Treatment of Hyperglycaemia with T2D Patients Part 3 (16:05)
Rating

This presentation focuses on the treatment of hyperglycaemia with type 2 diabetes patients. We’ll provide an introduction to exenatide, liraglutide, GLP-1 receptor antagonist, combination therapy, DPP-4 inhibitor, pancreatic safety of incretin-based drugs, SGLT-2 inhibitor and glucose absorption.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Sten Madsbad
Date Added:
01/07/2015
Diabetes - A Global Challenge - Treatment of Hyperglycaemia with T2D Patients Part 4 (07:32)
Rating

This presentation provides an introduction to Sodium-glucose linked transporter 2 inhibitors (SGLT-2) and how it affects the blood glucose. Furthermore we’ll discuss how SGLT-2 inhibitors can be used for treating patients with type 2 diabetes. Three SGLT-2 inhibitors have been approved: Dapa, Empa and Canagliflozin, for clinical use in patients with type 2 diabetes.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Sten Madsbad
Date Added:
01/07/2015
Diabetes - The Essential Facts - Can we Cure Diabetes ? (17:02)
Rating

This presentation focus on the question: can we cure diabetes? By interviewing different experts we will estimate how possible it is that we will find a cure for diabetes in the future. One of the main arguments is that we already have a cure, which is eating right and exercise, but the big question is whether people are willing to take this cure?

Narrator: Richard Steed.

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - The Essential Facts
Author:
Associate Professor Signe Sørensen Torekov
MD Nicolai Wewer Albrechtsen
Professor Jens Juul Holst
Professor Juleen Zierath
Professor Torben Hansen
Date Added:
01/07/2016
Diabetes - The Essential Facts - How to Fight the Global Epidemic (12:11)
Rating

This presentation discuss how we can fight the global diabetes epidemic. According to WHO (2016) the incidence and impacts of diabetes can largely be prevented or reduced with an approach that incorporates evidence-based, affordable, cost-effective, population-wide and multi-sector intervention. So which interventions should we prioritize as the most efficient interventions to fight the global diabetes epidemic?

Narrator: Richard Steed.

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - The Essential Facts
Author:
Associate Professor Signe Sørensen Torekov
MD Nicolai Wewer Albrechtsen
Professor Arne Astrup
Professor Jens Juul Holst
Professor Juleen Zierath
Professor Venkat Narayan
Date Added:
01/07/2016
Diabetes - The Essential Facts - Surgery, Drugs and Microchips (17:12)
Rating

Many people exercise and take medicine in order to delay or treat type 2 diabetes. However in most cases these interventions in one’s lifestyle fails and the person regain weight and retain their increasing blood glucose levels. Controlling one’s appetite seems to be the key, which is one of the aspects we’ll discuss in this presentation. Furthermore we’ll discuss how gastric bypass surgery helps people with diabetes type 2 controlling their appetite and make their diabetes disappear. Finally we’ll discuss how hormones such as GLP-1 can help diabetics’ control their appetite, and lose weight.

Narrator: Richard Steed.

Subject:
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
EIT
NNF Center for Basic Metabolic Research
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - The Essential Facts
Author:
Associate Professor Signe Sørensen Torekov
Dr Tricia Tan
MD Nicolai Wewer Albrechtsen
Professor Jens Juul Holst
Professor Steven Bloom
Date Added:
01/07/2016