This set of resources was developed and employed numerous times to help students clarify the frequent confusion about cells' chromosome number and ploidy level. It uses simplified stick diagrams to represent chromosomes and circles or oval to represent cells and includes a short, low-tech video tutorial that delivers the information, a worksheet that students can use to practice and test their understanding of the video materials, a set of clicker questions that address the same points as the worksheet, and instructor's notes.

The authors of the research presented in this special collection used the first description of the B73 maize genome to probe some of the most intriguing questions in genetics and plant biology. Read about maize centromeres, new insights into transposon types and distribution, the abundance of very short FLcDNAs encoding predicted peptides, and many other "genetic jewels" contained herein.

OER | Biology Overview:

On this webpage you will find OER Biology textbooks along with supplemental materials and a few lecture videos.
The purpose of these discipline-specific webpages is to display content that might be of interest to faculty who are considering adopting open educational resources for use in their classes. This list of content is by no means exhaustive. The nature of open educational resources is very collaborative and it is in that spirit that we encourage any comments about the content featured on this page or recommendations of content that are not already listed here.

Bioethics is the study of the moral implications of new and emerging medical technologies and looks to answer questions such as selling organs, euthanasia and whether should we clone people. The series consists of a series of interviews by leading bioethics academics and is aimed at individuals looking to explore often difficult and confusing questions surrounding medical ethics. The series lays out the issue in a clear and precise way and looks to show all sides of the debate.

This 28-minute video lesson provides an introduction to DNA. [Biology playlist: Lesson 6 of 71].

This site contains user-friendly tools to launch DNA database searches, statistical analyses, and population modeling from a centralized workspace. Educational databases support investigations of an Alu insertion polymorphism on human chromosome 16 and single nucleotide polymorphisms (SNPs) in the human mitochondrial control region.

This is a coloring book that I drew and designed as a fun way for my students to review information and/or doodle on. The pictures are inspired by images I use in my General Biology I class, and are presented in the same order as they are discussed in my class. The coloring book is NOT designed as an alternative to attending lecture, studying notes, etc.
You can download the PDF of the coloring book and then color the pictures on an app (like using an iPad and Apple Pencil) or print out the images and color them using your preferred method (like with colored pencils).

Host Harry Kreisler Welcomes Professor Sir John Gurdon for a discussion of advances in research on cell biology. Sir John reflects on his career as a scientist including his path breaking research on cloning. He offers insights into the implications of the revolution in the biological sciences.(46 min)

Explore the relationship between the genetic code on the DNA strand and the resulting protein and rudimentary shape it forms. Through models of transcription and translation, you will discover this relationship and the resilience to mutations built into our genetic code. Start by exploring DNA's double helix with an interactive 3D model. Highlight base pairs, look at one or both strands, and turn hydrogen bonds on or off. Next, watch an animation of transcription, which creates RNA from DNA, and translation, which 'reads' the RNA codons to create a protein.

Students learn the principles of independent assortment and gene linkage in activities which analyze inheritance of multiple genes on the same or different chromosomes in hypothetical dragons. Students learn how these principles derive from the behavior of chromosomes during meiosis and fertilization.

In this simulation activity students mimic the processes of meiosis and fertilization to investigate the inheritance of multiple genes and then use their understanding of concepts such as dominant/recessive alleles, incomplete dominance, sex-linked inheritance, and epistasis to interpret the results of the simulation. This activity can be used as a culminating activity after you have introduced classical genetics, and it can serve as formative assessment to identify any areas of confusion that require additional clarification.

Epigenetics - our epigenome - controls how our genes behave without altering their sequence. Just about everything affects it, from nutrition, drugs, and toxins to child rearing, culture, and society. Many diseases, from obesity to addiction to cancer, can be linked to epigenetic modifications. Furthermore, throughout development and life, from conception to death, the exposures you have will not only affect your own epigenome, but potentially also your child’s, and your grandchild’s. This rapidly expanding field of biological, physiological, sociological, and psychological research could be key to discovering why, and more importantly how, we are the way we are.

Epigenetics has consequences for medicine, pregnancy, childcare, law and how we live on an everyday basis. This book will provide a comprehensive introduction to the mechanisms and real-life consequences of epigenetics, and will arm the reader with the knowledge necessary to make informed decisions about the future of epigenetics in modern society. This is a call for serious consideration about the effects of epigenetics on society.

Instructional video on the formation of catenane after replication of circular bacterial chromosome.

Although textbooks describe this process and show illustrations, it is difficult to grasp without seeing a live demonstration.

Created for Biology 41 General Genetics at Tufts University.

For more than two decades J. Craig Venter and his research teams have been pioneers in genomic research. Regarded as one of the leading scientist of the 21st century, Venter discusses how he is applying tools and techniques developed to sequence the human genomes to discover new genes of microbes from around the world. (57 minutes)

This problem challenges students to design experiments using techniques measuring gene expression (reverse transcriptase PCR, microarrays, in situ hybridization).

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Genetic manipulation of crops is an issue of great current interest and controversy. This unit covers some of the basic science that underpins the debate and examines the hotly contested case study of the development of 'Golden Rice'. By looking at the science 'behind the headlines' you will acquire a clearer idea of both what is possible in GM science and what may be desirable.

This Unit looks at three different uses of genetic testing: pre-natal diagnosis, childhood testing and adult testing. Such tests provide genetic information in the form of a predictive diagnosis, and as such are described as predictive tests. Pre-natal diagnosis uses techniques such as amniocentesis to test fetuses in the womb. For example, it is commonly offered to women over 35 to test for Down's syndrome. Childhood testing involves testing children for genetic diseases that may not become a problem until they grow up, and adult testing is aimed at people at risk of late-onset disorders, which do not appear until middle age. In addition, we address some of the issues involved in carrier testing, another predictive test. This involves the testing of people from families with a history of genetic disease, to find out who carries the gene, and who therefore might pass the disease onto their children even though they themselves are unaffected. Here the aim is to enable couples to make informed choices about whether or not to have children, and if so whether they might have a genetic disease studies 'proteins'. Starting with a simple analysis of the molecular make up, the Unit moves on to look at the importance of protein and how they are digested and absorbed.

An integrated course stressing the principles of biology. Life processes are examined primarily at the molecular and cellular levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

The goal of the Genetic Origins Program is to allow students to use their own DNA variations (polymorphisms) as a means to explore our shared genetic heritage and its implications for human health and society. Genetic Origins focuses on two types of DNA variations: an Alu insertion polymorphism on chromosome 16 (PV92) and single nucleotide polymorphisms (SNPs) in the control region of the mitochondrial (mt) chromosome. With two alleles and three genotypes, PV92 is a simple genetic system that illustrates Mendelian inheritance on a molecular level. PV92 data is readily analyzed using population statistics. The mt control region is one of the simplest regions of human DNA to sequence. With a high mutation rate, the mt control region is the "classical" system for studying human and primate evolution. The Genetic Origins site and linked Bioservers site have all the information needed for students to perform the Alu and mt DNA experiments and analyze the results - including online protocols, reagents, animations and videos explaining key concepts, and database tools.