Keywords: Tissue Regeneration (3)

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Biomaterials-Tissue Interactions, Fall 2003
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Biomaterials-Tissue Interactions, Fall 2003

Principles of materials science and cell biology underlying the design of medical ... (more)

Principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological function for tissues and organs. (less)

Subject:
Science and Technology
Material Type:
Case Study
Full Course
Homework and Assignments
Lecture Notes
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Spector, Myron
ECM Remodeling Regulates Angiogenesis: Endothelial Integrins Look for New Ligands
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ECM Remodeling Regulates Angiogenesis: Endothelial Integrins Look for New Ligands

The process of angiogenesis is a dynamic one. Vascular endothelial cells are ... (more)

The process of angiogenesis is a dynamic one. Vascular endothelial cells are changing at the same time the extracellular matrix is being remodeled. Stupack and Cheresh discuss how remodeling of the extracellular matrix (ECM) and changes in the endothelial cell protein production and integrin expression contribute to the complex process of new blood vessel growth from an existing vascular bed. (less)

Subject:
Life Science
Material Type:
Activities and Labs
Images and Illustrations
Instructional Material
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David A. Cheresh (The Scripps Research Institute;Departments of Immunology and Vascular Biology REV)
Dwayne G. Stupack (The Scripps Research Institute;Departments of Immunology and Vascular Biology REV)
Reading the Blueprint of Life:  Transcription, Stem Cells and Differentiation, Fall 2006
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Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation, Fall 2006

In this course, we will address how transcriptional regulators both prohibit and ... (more)

In this course, we will address how transcriptional regulators both prohibit and drive differentiation during the course of development. How does a stem cell know when to remain a stem cell and when to become a specific cell type? Are there global differences in the way the genome is read in multipotent and terminally differentiated cells? We will explore how stem cell pluripotency is preserved, how master regulators of cell-fate decisions execute developmental programs, and how chromatin regulators control undifferentiated versus differentiated states. Additionally, we will discuss how aberrant regulation of transcriptional regulators produces disorders such as developmental defects and cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. (less)

Subject:
Science and Technology
Material Type:
Full Course
Homework and Assignments
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Guenther, Matthew
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2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

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