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Fiber utilization in the rumen of dairy cows: bacterial genomes and epithelial cell gene expression
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Ruminants’ ability to break down human-inedible plant fibers stems from the microbes in their rumen. This process is primarily driven by microbes that can ferment plant fibers into volatile fatty acids (VFAs), followed by the rumen epithelial layer absorbing and partially metabolizing these VFAs. Recently, researchers examined how microbes and epithelial cells interact and contribute to VFA metabolism in lactating dairy cows. Metagenomic binning allowed researchers to categorize and examine the metabolic capacity of even uncultivated microbes and identify bacterial genomes with both cellulose/xylan/pectin degradation capabilities and associations with VFA biosynthesis. They then used gene expression data to construct a single-cell map of the rumen epithelial cell subtypes. Searching gene expression profiles for VFA transporters highlighted key epithelial cell subtypes. Leveraging this data highlighted interactions where microbes potentially influenced the gene expression of host epithelial cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/17/2022
Kitchen Chemistry
Conditional Remix & Share Permitted
CC BY-NC-SA
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This seminar is designed to be an experimental and hands-on approach to applied chemistry (as seen in cooking). Cooking may be the oldest and most widespread application of chemistry and recipes may be the oldest practical result of chemical research. We shall do some cooking experiments to illustrate some chemical principles, including extraction, denaturation, and phase changes.

Subject:
Chemistry
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Christie, Patricia
Date Added:
02/01/2009
Microbe-diet interactions influence the effects of fiber on host metabolism
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Human microbiomes are diverse and dynamic communities of bacteria, which play a critical role in many aspects of human health, including the breakdown of the food we eat. Research has shown that dietary fermentable fiber generally improves cardiometabolic health. However, past studies have found the response to specific interventions has significant variation between individuals. This variation likely has multiple causes, but the role of gut microbial metabolism has not yet been explored. To test this, researchers colonized germ free (GF) mice with distinct, complex microbial communities and then fed them one of four diets. Each microbiome remained distinct under all diets, but the different diets led to variations in richness and taxon abundance in both microbiomes. Epigenetic, transcriptional, and metabolic analyses showed diet-directed differences between the communities, including changes in metabolic pathways associated with health..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/13/2021
Paper making
Conditional Remix & Share Permitted
CC BY-NC-SA
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In this activity, learners explore the question "What is paper?" Learners discover the processes and materials required to make paper while experimenting with different recycled fibers and tools.

Subject:
Physical Science
Material Type:
Activity/Lab
Provider:
Exploratorium
Author:
Don Rathjen
Ellen Koivisto
The Exploratorium
Date Added:
10/31/2012