Keywords: Mutant (7)

save
save to

Please log in to save materials.

selected filters:
The DNA Damage Response as a Target for Anti-Cancer Therapy, Fall 2008
Remix and Share

The DNA Damage Response as a Target for Anti-Cancer Therapy, Fall 2008

Cellular responses to DNA damage constitute one of the most important fields ... (more)

Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand of cell cycle regulation and DNA damage checkpoints that act as powerful emergency brakes to prevent cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. (less)

Subject:
Science and Technology
Material Type:
Full Course
Homework and Assignments
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Reinhardt, Hans Christian
DNA Methylation and Epigenetic Inheritance in Plants and Filamentous Fungi
Read the Fine Print

DNA Methylation and Epigenetic Inheritance in Plants and Filamentous Fungi

Plants and filamentous fungi share with mammals enzymes responsible for DNA methylation. ... (more)

Plants and filamentous fungi share with mammals enzymes responsible for DNA methylation. In these organisms, DNA methylation is associated with gene silencing and transposon control. However, plants and fungi differ from mammals in the genomic distribution, sequence specificity, and heritability of methylation. We consider the role that transposons play in establishing methylation patterns and the epigenetic consequences of their perturbation. (less)

Subject:
Life Science
Education
Material Type:
Images and Illustrations
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Robert A. Martienssen (Cold Spring Harbor Laboratory;)
Vincent Colot (Cold Spring Harbor Laboratory;)
Experimental Microbial Genetics, Fall 2008
Remix and Share

Experimental Microbial Genetics, Fall 2008

" In this class, students engage in independent research projects to probe ... (more)

" In this class, students engage in independent research projects to probe various aspects of the physiology of the bacteriumĺĘPseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production. Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notice " (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Full Course
Homework and Assignments
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Croal, Laura
Laub, Michael
Melvold, Janis
Newman, Dianne
Genes for memory (lesson)
Read the Fine Print

Genes for memory (lesson)

Students will experiment with an interactive animation to compare mutant and wild-type ... (more)

Students will experiment with an interactive animation to compare mutant and wild-type mice in a water maze. They will analyze data and discuss findings of a research paper. (less)

Subject:
Geoscience
Life Science
Social Sciences
Education
Material Type:
Instructional Material
Readings
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Amy Nisselle REV
Caren Gough TITLE
Danielle Sixsmith NOTE;ENCODING=QUOTED-PRINTABLE
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
John Connolly (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Laura Maitland (Mepham High School TITLE)
Mary Colvard TITLE
Mutant Cockroaches
Read the Fine Print

Mutant Cockroaches

Images of mutant cockroaches, provided by the Genetic Stock Center for the ... (more)

Images of mutant cockroaches, provided by the Genetic Stock Center for the German Cockroach at Virginia Tech. Useful as a visual aid for explaining the effects of mutation. A linkage map is also available. (less)

Subject:
Life Science
Material Type:
Images and Illustrations
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Mutant Screens
Read the Fine Print

Mutant Screens

Doctor Josh Dubnau explains that mutant screens generate a large panel of ... (more)

Doctor Josh Dubnau explains that mutant screens generate a large panel of mutant animals that average a mutation in one gene. Each animal is then tested for a particular characteristic. (less)

Subject:
Chemistry
Life Science
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Amy Nisselle REV
Caren Gough TITLE
Danielle Sixsmith NOTE;ENCODING=QUOTED-PRINTABLE
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
John Connolly (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Laura Maitland (Mepham High School TITLE)
Mary Colvard TITLE
Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats
Read the Fine Print

Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats

Common patterns found in cheetahs and house cats suggest a shared mechanism ... (more)

Common patterns found in cheetahs and house cats suggest a shared mechanism for creating their parti-colored coats. In this paper, Kaelin et al. use histology, genomic expression studies, and transgenic mice to unravel the relationship between the Taqpep gene and periodic coat patterns in felids. (less)

Subject:
Life Science
Education
Material Type:
Images and Illustrations
Instructional Material
Lesson Plans
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Anne Schmidt-K퀌_ntzel (Frederick National Laboratory for Cancer Research; Cheetah Conservation Fund;Laboratory of Genomic Diversity)
Ann van Dyk (The Ann van Dyk Cheetah Centre, De Wildt, South Africa;)
Bisong Yue (Sichuan University;Sichuan Key Laboratory of Conservation Biology on Endangered Wildlife, College of Life Sciences)
Christopher B. Kaelin (HudsonAlpha Institute for Biotechnology; Stanford University;)
Cindy K. Harper (University of Pretoria, Pretoria, South Africa.;Veterinary Genetics Laboratory, Faculty of Veterinary Science Onderstepoort)
Eduardo Eizirik (Pontif퀌_cia Universidade Cat퀌_lica do Rio Grande do Sul; Instituto Pr퀌_-Carn퀌_voros;Faculdade de Bioci퀌Čncias)
Gregory M. Cooper (HudsonAlpha Institute for Biotechnology;)
Gregory S. Barsh (HudsonAlpha Institute for Biotechnology; Stanford University;Department of Genetics)
Hermogenes Manuel (Stanford University;Department of Genetics)
James C. Mullikin (National Institutes of Health;Comparative Genomics Unit, National Human Genome Research Institute)
Javier Pino (Florida International University;Department of Biological Sciences)
Joan Pontius (Frederick National Laboratory for Cancer Research;Laboratory of Genomic Diversity; SAIC-Frederick)
Kelly A. McGowan (Stanford University;Department of Genetics)
Laurie Marker (Cheetah Conservation Fund;)
Lewis Z. Hong (Stanford University;Department of Genetics)
Lidia Kos (Florida International University;Department of Biological Sciences)
Marilyn Menotti-Raymond (Frederick National Laboratory for Cancer Research;Laboratory of Genomic Diversity)
Melody E. Roelke (Frederick National Laboratory for Cancer Research;Laboratory of Genomic Diversity; SAIC-Frederick)
Stephen J. Oí˘ŒóŒťBrien (Frederick National Laboratory for Cancer Research;Laboratory of Genomic Diversity)
Victor A. David (Frederick National Laboratory for Cancer Research;Laboratory of Genomic Diversity)
Wesley C. Warren (Washington University in St. Louis;The Genome Center)
William F. Swanson (Cincinnati Zoo & Botanical Garden;Center for Conservation and Research of Endangered Wildlife)
Xiao Xu (Frederick National Laboratory for Cancer Research; Sichuan University;Laboratory of Genomic Diversity, Sichuan Key Laboratory of Conservation Biology on Endangered Wildlife, College of Life Sciences)
2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni ... (more)

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni smelborp gnivlos rof seuqinhcet gnipoleved no si sisahpmE .scipot decnavda detceles dna scihparg retupmoc ,gnihcraes dna gnitros ,serutcurts atad ,sdohtem laciremun ,secafretni resu lacihparg ,stpecnoc gnimmargorp revoc smelborp gnimmargorp ylkeeW .esruoc eht fo sucof eht si tnempoleved dna ngised erawtfos detneiro-tcejbO .snoitacilppa cifitneics dna gnireenigne rof sdohtem lanoitatupmoc dna tnempoleved erawtfos latnemadnuf stneserp esruoc sihT (less)