Keywords: Genetic Disease (12)

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Case It! Case Study Learning via Simulations of Molecular Biology Techniques
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Case It! Case Study Learning via Simulations of Molecular Biology Techniques

Case It! is an NSF-sponsored project to promote collaborative case-based learning in ... (more)

Case It! is an NSF-sponsored project to promote collaborative case-based learning in biology education worldwide. This paper describes the latest version of the Case It! simulation software (DNA gel electrophoresis, Southern blotting, and PCR). Students use these open-ended molecular biology computer simulations to analyze case studies involving genetic diseases, then discuss results with their peers at other institutions via web-based "poster sessions." They also use Case It! software to gather background information, analyze DNA and protein sequences, then create web-page posters and discuss them via a web editor /conferencing system at the Case It! web site (http://www.uwrf.edu/caseit/caseit.html). (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Case Study
Lesson Plans
Provider:
University of Wisconsin-River Falls
Provider Set:
Association for Biology Laboratory Education (ABLE)
Author:
Karen Klyczek
Mark Bergland
Case Study: Brain vs. Spinal Cord
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Case Study: Brain vs. Spinal Cord

This is a case study for high school and undergraduate students in ... (more)

This is a case study for high school and undergraduate students in anatomy and physiology. In particular this case study explores anatomy of the cardiovascular and muscular systems. Users of the National Center for Case Study Teaching in Science will be required to register (free) to gain access to the answer key (and must be of teaching status to receive the key). Included in the resource are the case overview, objectives, case study, teaching notes and answer key. (less)

Subject:
Social Sciences
Education
Material Type:
Activities and Labs
Instructional Material
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Michael Hudecki (University of Buffalo Biological Sciences)
Thomas Cappaert (Central Michigan University Physical Education and Sport)
Causes, Inheritance
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Causes, Inheritance

All cancers are genetic, in that cancers are caused by genetic mutations ... (more)

All cancers are genetic, in that cancers are caused by genetic mutations in genes that lead to malignancy. (less)

Subject:
Life Science
Education
Material Type:
Instructional Material
Interactive
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
John Connolly (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Laura Maitland (Mepham High School TITLE)
Causes, Inheritance: Cancer gene types
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Causes, Inheritance: Cancer gene types

This section identifies that a cancer gene alters the normal functioning of ... (more)

This section identifies that a cancer gene alters the normal functioning of a protein, and there are three major categories of cancer genes. (less)

Subject:
Life Science
Education
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
John Connolly (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Laura Maitland (Mepham High School TITLE)
Causes, Inheritance: Cancer gene types, Vogelstein clip 2
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Causes, Inheritance: Cancer gene types, Vogelstein clip 2

Professor Vogelstein, explains that cancer is in essence a genetic disease. But ... (more)

Professor Vogelstein, explains that cancer is in essence a genetic disease. But it's really quite different than all the other genetic diseases that people usually think of when they think about a genetic disease. (less)

Subject:
Life Science
Education
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
John Connolly (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Laura Maitland (Mepham High School TITLE)
Chromosome 13: BRCA2 gene for breast cancer susceptibility, Matt RidleySite: DNA Interactive (www.dnai.org)
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Chromosome 13: BRCA2 gene for breast cancer susceptibility, Matt RidleySite: DNA Interactive (www.dnai.org)

Interviewee: Matt Ridley DNAi Location:Genome>tour>Genome spots>Breast cancer Location: chromosome 13 gene name: ... (more)

Interviewee: Matt Ridley DNAi Location:Genome>tour>Genome spots>Breast cancer Location: chromosome 13 gene name: BRCA2 (breast cancer 2) BRCA2, on chromosome 13, is one of the genes associated with hereditary breast cancer. Although gender, age and environmental effects are major risk factors for breast cancer, having a mutation in either the BRCA2 gene or BRCA1 gene (on chromosome 17) increases the risk. (less)

Subject:
History, Law, Politics
Chemistry
Life Science
Education
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
Chromosome 8: transposable elements, Matt RidleySite: DNA Interactive (www.dnai.org)
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Chromosome 8: transposable elements, Matt RidleySite: DNA Interactive (www.dnai.org)

Interviewee: Matt Ridley

Subject:
History, Law, Politics
Chemistry
Life Science
Education
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
Ethics and Reproductive Issues: The Dilemma of Choice
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Ethics and Reproductive Issues: The Dilemma of Choice

This Science NetLinks lesson introduces students to the ethical implications of using ... (more)

This Science NetLinks lesson introduces students to the ethical implications of using our growing knowledge about the human genome to improve our personal and public health. Students will be asked to consider numerous ethical issues related to genetic testing and will find that there are no easy answers. Most importantly, students will learn that there is no one "answer" to an ethical question; rather, there exist a multitude of perspectives that must be taken into account. Ultimately, students will learn that making an ethical choice requires scientific knowledge and rational inquiry. (less)

Subject:
Life Science
Technology
Social Sciences
Education
Material Type:
Instructional Material
Lesson Plans
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Science Netlinks;
Genomic Medicine, Spring 2004
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Genomic Medicine, Spring 2004

This course reviews the key genomic technologies and computational approaches that are ... (more)

This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be? (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Audio Lectures
Full Course
Homework and Assignments
Lecture Notes
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Kohane, Isaac
Katreece, sickle cell patient, still imageSite: DNA Interactive (www.dnai.org)
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Katreece, sickle cell patient, still imageSite: DNA Interactive (www.dnai.org)

Katreece (here at right) has sickle cell anemia. The causes of sickle ... (more)

Katreece (here at right) has sickle cell anemia. The causes of sickle cell have been known since the 1940s. (less)

Subject:
Chemistry
Life Science
Material Type:
Images and Illustrations
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
Shutting down cancer with Gleevec퉌ť, Brian DrukerSite: DNA Interactive (www.dnai.org)
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Shutting down cancer with Gleevec퉌ť, Brian DrukerSite: DNA Interactive (www.dnai.org)

Interviewee: Brian Druker DNAi Location:Applications>Genes and medicine>drug design Shutting down cancer Brian ... (more)

Interviewee: Brian Druker DNAi Location:Applications>Genes and medicine>drug design Shutting down cancer Brian Druker reflects on the importance of understanding the causes of cancer for developing new treatments. (less)

Subject:
History, Law, Politics
Chemistry
Life Science
Social Sciences
Education
Material Type:
Instructional Material
Video Lectures
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
Sickle cell anemia, 3D animation with narrationSite: DNA Interactive (www.dnai.org)
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Sickle cell anemia, 3D animation with narrationSite: DNA Interactive (www.dnai.org)

DNAi Location:Genome>Tour>genome spots>Sicke cell>About sickle cell Sickle cell anemia is a genetic ... (more)

DNAi Location:Genome>Tour>genome spots>Sicke cell>About sickle cell Sickle cell anemia is a genetic disease that affects hemoglobin, the oxygen transport molecule in the blood. The disease gets its name from to the shape of the red blood cells under certain conditions. Some red blood cells become sickle-shaped and these elongated cells get stuck in small blood vessels so that parts of the body don't get the oxygen they need. Sickle cell anemia is caused by a single code letter change in the DNA. This in turn alters one of the amino acids in the hemoglobin protein. Valine sits in the position where glutamic acid should be. The valine makes the hemoglobin molecules stick together, forming long fibers that distort the shape of the red blood cells, and this brings on an attack. (less)

Subject:
Mathematics
Chemistry
Life Science
Material Type:
Images and Illustrations
Instructional Material
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David Micklos (Cold Spring Harbor Laboratory;DNA Learning Center X-AUDIENCE)
Elof Carlson (SUNY at Stony Brook;Biology Department X-AUDIENCE)
Garland Allen (Washington University at St. Louis;Biology Department X-AUDIENCE)
Jan Witkowski (Cold Spring Harbor Laboratory;Banbury Center X-AUDIENCE)
Paul Lombardo (University of Virginia;Center for Biomedical Ethics X-AUDIENCE)
Steven Selden (University of Maryland;Education Policy and Leadership Department X-AUDIENCE)
2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni ... (more)

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni smelborp gnivlos rof seuqinhcet gnipoleved no si sisahpmE .scipot decnavda detceles dna scihparg retupmoc ,gnihcraes dna gnitros ,serutcurts atad ,sdohtem laciremun ,secafretni resu lacihparg ,stpecnoc gnimmargorp revoc smelborp gnimmargorp ylkeeW .esruoc eht fo sucof eht si tnempoleved dna ngised erawtfos detneiro-tcejbO .snoitacilppa cifitneics dna gnireenigne rof sdohtem lanoitatupmoc dna tnempoleved erawtfos latnemadnuf stneserp esruoc sihT (less)