Keywords: Eukaryotes (12)

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Antibiotics, Toxins, and Protein Engineering, Spring 2007
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Antibiotics, Toxins, and Protein Engineering, Spring 2007

The lethal poison Ricin (best known as a weapon of bioterrorism), Diphtheria ... (more)

The lethal poison Ricin (best known as a weapon of bioterrorism), Diphtheria toxin (the causative agent of a highly contagious bacterial disease), and the widely used antibiotic tetracycline have one thing in common: They specifically target the cell's translational apparatus and disrupt protein synthesis. In this course, we will explore the mechanisms of action of toxins and antibiotics, their roles in everyday medicine, and the emergence and spread of drug resistance. We will also discuss the identification of new drug targets and how we can manipulate the protein synthesis machinery to provide powerful tools for protein engineering and potential new treatments for patients with devastating diseases, such as cystic fibrosis and muscular dystrophy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. (less)

Subject:
Science and Technology
Material Type:
Full Course
Homework and Assignments
Lecture Notes
Syllabi
Provider:
M.I.T.
Provider Set:
MIT OpenCourseWare
Author:
Sassanfar, Mandana
Cosmology and Astronomy: Beginnings of Life (2): Ozone Layer and Eukaryotes Show Up in the Proterozoic Eon
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Cosmology and Astronomy: Beginnings of Life (2): Ozone Layer and Eukaryotes Show Up in the Proterozoic Eon

This 10-minute video lesson contiues to discuss the beginnings of life on ... (more)

This 10-minute video lesson contiues to discuss the beginnings of life on Earth. The ozone layer and eukaryotes show up in the proterozoic eon. It includes the great oxygenation event (oxygen catastrophe). [Cosmology and Astronomy playlist: Lesson 40 of 85] (less)

Subject:
Science and Technology
Material Type:
Video Lectures
Provider:
Khan Academy
Provider Set:
Khan Academy
Author:
Khan, Salman
The Discovery of Penicillin
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The Discovery of Penicillin

This video segment adapted from A Science Odyssey tells the story of ... (more)

This video segment adapted from A Science Odyssey tells the story of researcher Sir Alexander Fleming, whose luck and scientific reasoning led to the groundbreaking discovery of penicillin. ***Access to Teacher's Domain content now requires free login to PBS Learning Media. (less)

Subject:
History, Law, Politics
Science and Technology
Life Science
Material Type:
Video Lectures
Provider:
PBS LearningMedia
PBS Learning Media
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Teachers' Domain
Author:
Lawrence Hall of Science
WGBH Educational Foundation
Evolution of the Molecular Machines for Protein Import into Mitochondria
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Evolution of the Molecular Machines for Protein Import into Mitochondria

This article discusses the way in which protein import pathways were established ... (more)

This article discusses the way in which protein import pathways were established to create mitochondria. In creating mitochondria some 2 billion years ago, the first eukaryotes needed to establish protein import machinery in the membranes of what was a bacterial endosymbiont. Some of the preexisting protein translocation apparatus of the endosymbiont appears to have been commandeered, including molecular chaperones, the signal peptidase, and some components of the protein-targeting machinery. However, the protein translocases that drive protein import into mitochondria have no obvious counterparts in bacteria, making it likely that these machines were created de novo. The presence of similar translocase subunits in all eukaryotic genomes sequenced to date suggests that all eukaryotes can be considered descendants of a single ancestor species that carried an ancestral í˘ŒóŒěprotomitochondria.í˘ŒóŒ (less)

Subject:
Life Science
Material Type:
Data
Images and Illustrations
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Jan Tachezy (Charles University;Department of Parasitology)
Pavel Dolezal (University of Melbourne, Bio21 Molecular Science and Biotechnology Institute;Department of Biochemistry & Molecular Biology)
Trevor Lithgow (University of Melbourne, Bio21 Molecular Science and Biotechnology Institute;Department of Biochemistry & Molecular Biology)
Vladimir Lakic (Bio21 Molecular Science and Biotechnology Institute;)
The Human Cell (03:02): Eukaryotes vs. Prokaryotes

The Human Cell (03:02): Eukaryotes vs. Prokaryotes

Our second video from the cell biology lesson, part of our anatomy ... (more)

Our second video from the cell biology lesson, part of our anatomy and physiology lecture series. This video gives a brief summary of the differences between eukaryotes and prokaryotes. All of our videos can be found at http://www.mrfordsclass.net The concepts covered in this video include: •Eukaryotes •Prokaryotes (less)

Subject:
Science and Technology
Material Type:
Video Lectures
Provider:
Mr. Ford's Class
Author:
Scott Ford
Microbiology
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Microbiology

This course will cover a range of diverse areas of microbiology, including ... (more)

This course will cover a range of diverse areas of microbiology, including virology, bacteriology, and even applied microbiology. This course will focus on the medical aspects of microbiology, as medical research has been the primary motivator in microbiology research. Upon successful completion of this course, the student will be able to: explain how organisms are classified using taxonomy, focusing on the domains Archaea, Bacteria, and Eukarya; describe the chemical building blocks and metabolic processes important to sustain microbial life; identify the major principles of microbiology and describe the relationship between microbes and other living organisms; discuss pathogenic microbes and their epidemiology; differentiate between microorganisms based on their shape, size, arrangement, staining, and culture characteristics; outline antimicrobial methods including antibiotic use; explain how the human body protects itself; list uses for microbiology in food and beverage preparation and industry. (Biology 307) (less)

Subject:
Science and Technology
Material Type:
Assessments
Audio Lectures
Full Course
Lecture Notes
Readings
Syllabi
Video Lectures
Provider:
The Saylor Foundation
Provider Set:
Saylor Foundation
Mi nombre es LUCA í˘ŒóŒń El 퀌_ltimo Ancestro Universal Com퀌_n
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Mi nombre es LUCA í˘ŒóŒń El 퀌_ltimo Ancestro Universal Com퀌_n

Looking down a microscope at a human cell, there is not a ... (more)

Looking down a microscope at a human cell, there is not a lot that it seems to share in common with a bacterial cell. But just as linguists have been able to establish that all human languages have a common origin, so it turns out that all cellular life has a common origin. The ancestor of all life on Earth today has been dubbed LUCA, short for Last Universal Common Ancestor. The fact that there must have been a LUCA was first made clear in the 1960s when the genetic code was deciphered and found to be universal. Almost forty years since the code was cracked, the emphasis is now on trying to reconstruct LUCA, but the emerging picture is substantially complicated by new insights into the evolutionary history of life. (less)

Subject:
Mathematics
Life Science
Material Type:
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Anthony Poole (Stockholm University;)
Molecular Tools for Discovering the Secrets of Diatoms
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Molecular Tools for Discovering the Secrets of Diatoms

Diatoms are photosynthetic unicellular eukaryotes found in most aquatic environments. They are ... (more)

Diatoms are photosynthetic unicellular eukaryotes found in most aquatic environments. They are major players in global biogeochemical cycles, and generate as much oxygen through photosynthesis as terrestrial rainforests do. Insights into their evolutionary origins have been revealed by the whole-genome sequencing of Thalassiosira pseudonana and Phaeodactylum tricornutum. We now know that diatoms contain unusual assortments of genes derived from different sources, including those acquired by horizontal gene transfer from bacteria. These genes confer novel metabolic and signaling capacities that may underlie the extraordinary ecological success of diatoms on Earth today. The availability of a suite of techniques that can be used to monitor and manipulate diatom genes is enhancing our knowledge of their novel characteristics. We highlight these recent developments and illustrate how they are being used to understand different aspects of diatom biology. We also discuss the use of diatoms in commercial applications, such as for nanotechnology and biofuel production. (less)

Subject:
Engineering
Life Science
Technology
Material Type:
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Anastasia Saade (퀌Šcole Normale Sup퀌Šrieure in Paris;Department of Biology)
Chris Bowler (퀌Šcole Normale Sup퀌Šrieure in Paris;Department of Biology)
Prokaryotes and Eukaryotes  (Interactive Animation)
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Prokaryotes and Eukaryotes (Interactive Animation)

All living organisms are classified into two broad categories, prokaryotes & eukaryote. ... (more)

All living organisms are classified into two broad categories, prokaryotes & eukaryote. Prokaryotes are those organisms whose cells lack a cell nucleus while eukaryotes possess a well-defined, membrane bound nucleus. (less)

Subject:
Science and Technology
Material Type:
Interactive
Provider:
Indian Institute of Technology Bombay
Provider Set:
Project OSCAR
Author:
Deepa John, Harini Chandra,Prof. Sanjeeva Srivastava
iBioSeminar: Apicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles
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iBioSeminar: Apicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles

There are more than 5000 species of single-celled eukaryotes in the biological ... (more)

There are more than 5000 species of single-celled eukaryotes in the biological phylum known as the Apicomplexa, including the parasites responsible for malaria, neurological birth defects, and opportunistic infections associated with HIV/AIDS. These ancient protozoa provide a unique window into the evolution of subcellular organelles that have long fascinated cell biologists. Familiar features help to elucidate the origins, functions and design parameters for the secretory pathway, endosymbiotic organelles, the cytoskeleton, and cell cycle control. Conversely, parasite-specific organelles highlight the evolutionary diversity of eukaryotes, and suggest novel targets for treating disease. (less)

Subject:
Life Science
Material Type:
Instructional Material
Lecture Notes
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
David S. Roos (University of Pennsylvania and Penn Genomics Institute;Department of Biology)
퉌ËCu퀌çl es el 퀌_ltimo Ancestro Universal Com퀌_n(LUCA)?
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퉌ËCu퀌çl es el 퀌_ltimo Ancestro Universal Com퀌_n(LUCA)?

LUCA, the last universal common ancestor, is still an enigma but scientists ... (more)

LUCA, the last universal common ancestor, is still an enigma but scientists have been able to: find more answers in the genetic code; and revise and reconstruct evolutionary trees; understand more about the role of gene swapping in evolution. (less)

Subject:
Life Science
Material Type:
Reference
Provider:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Provider Set:
BiosciEdNet (BEN): Digital Library Portal for Teaching and Learning in the Biological Sciences
Author:
Anthony Poole (Stockholm University;)
2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

2002 llaF ,gnivloS melborP gnireenignE dna sretupmoC ot noitcudortnI

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni ... (more)

.desu si egaugnal gnimmargorp avaJ ehT .gninnalp dna ,tnemeganam ,ecneics ,gnireenigne ni smelborp gnivlos rof seuqinhcet gnipoleved no si sisahpmE .scipot decnavda detceles dna scihparg retupmoc ,gnihcraes dna gnitros ,serutcurts atad ,sdohtem laciremun ,secafretni resu lacihparg ,stpecnoc gnimmargorp revoc smelborp gnimmargorp ylkeeW .esruoc eht fo sucof eht si tnempoleved dna ngised erawtfos detneiro-tcejbO .snoitacilppa cifitneics dna gnireenigne rof sdohtem lanoitatupmoc dna tnempoleved erawtfos latnemadnuf stneserp esruoc sihT (less)