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Diabetes - A Global Challenge - Novel Approaches in Drug Development Part 1 (11:09)
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CC BY-NC-ND
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This presentation focuses on the current and novel approaches used to develop drugs in the treatment of obesity. We’ll introduce the student to the physiological regulation of appetite and satiety in relation to meals, then we’ll provide an short overview of the previous and current treatment on the market for the treatment of obesity and finally we’ll describe some of the promising novel approaches pursued for future treatment.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Professor Birgitte Holst
Date Added:
01/07/2015
From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The balance between hunger and satiety plays a key role in metabolic health. Specifically, disrupted appetite can lead to eating disorders or obesity. Appetite control is influenced by a complex web of factors - including our gut microbiota. Gut microbiota influence appetite through a variety of mechanisms, including regulating appetite-related hormones such as leptin, ghrelin, and insulin, influencing the immune system and acting directly on hypothalamic neurons. Recently, there has been interest in exploring the gut-microbiota-brain axis in several research fields. Some research has suggested that the gut microbiota can regulate host body weight and even psychiatric disorders, but the effects of gut microbiome interventions have been inconsistent and require more research. Overall, there are many links between gut microbiota and host appetite, but the interaction is complicated by many outside variables, and the precise mechanisms have yet to be fully deciphered..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/13/2021
Gender, Sexuality, and Society
Conditional Remix & Share Permitted
CC BY-NC-SA
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This course seeks to examine how people experience gender - what it means to be a man or a woman - and sexuality in a variety of historical and cultural contexts. We will explore how gender and sexuality relate to other categories of social identity and difference, such as race and ethnicity, economic and social standing, urban or rural life, etc. One goal of the class is to learn how to critically assess media and other popular representations of gender roles and stereotypes. Another is to gain a greater sense of the diversity of human social practices and beliefs in the United States and around the world.

Subject:
Anthropology
Gender and Sexuality Studies
Social Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Paxson, Heather
Date Added:
02/01/2006
The Role of Genetics in Obesity
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Educational Use
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In this video segment from NOVA scienceNOW, meet researchers who are studying obesity and trying to understand the role that hormones and genetics can play in regulating appetite.

Subject:
Life Science
Material Type:
Lecture
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
The William and Flora Hewlett Foundation
WGBH Educational Foundation
Date Added:
08/26/2008