This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer. One of the distinguishing features of HCC tumors is their dense network of blood vessels. This makes Angiopoetin-2, a protein that promotes vessel formation in tumors, an attractive target for fighting HCC. In a recent study, researchers discovered a novel route HCC tumors use to release Angiopoetin-2. Test-tube experiments revealed that tumor cells wrapped Angiopoetin-2 in tiny sacs called exosomes. and delivered them to cells derived from human umbilical cord, which boosted blood vessel formation. Gene editing allowed the team to knock out the gene controlling Angiopoetin-2, which, once delivered, significantly reduced the generation of new lifelines from healthy cells. The results point to a new way of disrupting tumor growth. and could lead to new therapies for cancer of the liver and other organs..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Biology
- Life Science
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 04/29/2020