This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"New research shows that hyperalgesia, a neuropathic condition causing heightened sensitivity to pain, can be effectively reversed in a human experimental model. For the hundreds of thousands who suffer from this hard-to-treat condition, the study’s findings could offer much-needed pain relief. Treating neuropathic pain is notoriously difficult. Clinicians must wade through numerous patient-reported symptoms just to source the pain. And even when the presence of neuropathy is established, finding a treatment that works can be painstaking. In recent years, researchers have focused on neural receptors of N-methyl-D-aspartate, or NMDA; these receptors are linked to the central sensitization that gives rise to hyperalgesia. Specifically, they’ve explored the effects of NMDA receptor antagonists, such as ketamine, memantine, and dextromethorphan. Dextromethorphan has proven especially effective in combating hyperalgesia..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Applied Science
- Health, Medicine and Nursing
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 09/23/2019