This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"A new study in rhesus monkeys clarifies one aspect of how the new drug cebranopadol relieves pain and finds that this effective analgesic has milder side effects than fentanyl and morphine. Pure mu opioid receptor agonists like fentanyl and morphine are the most widely used analgesic drugs in medical settings. However, their severe side effects and high abuse potential have prompted the need for alternatives. Treatment with drugs that simultaneously target nociceptin receptors and mu receptors has been shown to limit mu receptor-related side effects. Cebranopadol, an effective pain reliever in rodents and humans, targets nociceptin receptors and various opioid receptors. But whether the mu opioid receptor subtype is the most important for cebranopadol analgesia is unknown, and the associated side effects haven’t been investigated in nonhuman primate models. To better evaluate cebranopadol as an analgesic alternative to pure mu agonists, researchers compared it with fentanyl and morphine..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
By the end of this section, you will be able to:Distinguish between …
By the end of this section, you will be able to:Distinguish between the two major cell types of the nervous system, neurons and gliaIdentify the basic parts of a neuron
Psychology is designed to meet scope and sequence requirements for the single-semester …
Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan
By the end of this section, you will be able to:Identify the …
By the end of this section, you will be able to:Identify the basic parts of a neuronDescribe how neurons communicate with each otherExplain how drugs act as agonists or antagonists for a given neurotransmitter system
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