This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"HIV affects 38 million people worldwide, and a cure remains elusive. One important factor in transmission and pathogenesis lies outside the virus: the microbiome of the gut and genital surfaces is increasingly recognized as a key player during HIV infection, affecting inflammation and microbial translocation. In an effort to better understand the effects of microbes on health during infection, researchers turned to an animal model. Vervet monkeys are a natural host for a closely related virus, simian immunodeficiency virus (SIV). Because they have faced SIV for hundreds of thousands of years, the monkeys have co-evolved with the virus, allowing vervets to have nonprogressive SIV infection. By evaluating the microbiota of SIV-infected vervets, the researchers sought to determine what microbe-associated factors protected vervets against AIDS. Characterization of fecal, rectal, vaginal, and penile microbiomes in vervets from heavily SIV-infected areas in South Africa..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Biology
- Life Science
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 02/25/2021