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- Author:
-
jlfink
- Subject:
- Science and Technology
- Institution Name:
- SciVee
- Collection:
-
SciVee
- Grade Level:
- Post-secondary
- Abstract:
We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for ~40% of the mouse proteome.
- Languages:
- English
- Media Format:
- Audio
- Conditions of Use:
-
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