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Genome Variation at the Basepair Level - Prof. Aleks MilosavljevicGenome Variation at the Basepair Level - Prof. Aleks Milosavljevic

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Author:
Subject:
Science and Technology
Institution Name:
SciVee
Collection:
SciVee
Grade Level:
Post-secondary
Abstract:

Insights into cancer biology from the study of base pair-level changes in coding sequences. Genotyping vs. resequencing. Identifying cancer-related genes using association studies. Use of next-generation sequencing technologies to map chromosomal aberrations in cancer genomes. PCR-based resequencing vs. array-based enrichment. Using recurrence, pathway enrichment, and other signatures of positive selection to identify "driver" somatic mutations involved in cancer progression. Part of the Computer-Aided Discovery Methods course taught at Baylor College of Medicine

Languages:
English
Media Format:
Video
Conditions of Use:
Creative Commons Attribution 3.0
Creative Commons Attribution 3.0

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