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Regulation of Blood Glucose Levels in Normal and Diabetic Rats

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Author:
Subject:
Science and Technology
Institution Name:
University of Texas
Collection:
Association for Biology Laboratory Education (ABLE)
Grade Level:
Post-secondary
Abstract:

This exercise demonstrates the crucial role insulin plays in blood glucose homeostasis in mammals. Three pairs of fasted rats are tested in each of three different regimes; one rat of each pair is normal and the other is diabetic. The first pair is administered an oral glucose load and a placebo injection of saline. The second pair is administered an oral glucose load and an insulin injection. The third pair is administered an oral placebo of water and a placebo injection of saline. The blood glucose levels of the six rats are monitored at 20-minute intervals for 2 hours by taking blood samples from each rat's tail.

Course Type:
Learning Module
Languages:
English
Material Type:
Activities and Labs, Lesson Plans
Media Format:
Downloadable docs
Conditions of Use:
Custom Permissions
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the copyright owner. Use solely at one's own institution with no intent for profit is excluded from the preceding copyright restriction, unless otherwise noted on the copyright notice of the individual chapter in this volume. Proper credit to this publication must be included in your laboratory outline for each use; a sample citation is given [on the copyright page of each volume]. Upon obtaining permission or with the "sole use at one's own institution" exclusion, ABLE strongly encourages individuals to use the exercises in this proceedings volume in their teaching program.

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