Protein Folding Problem, Fall 2007
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- Author:
- King, Jonathan
- Subject:
- Science and Technology
- Institution Name:
- M.I.T.
- Collection:
- MIT OpenCourseWare
- Grade Level:
- Post-secondary
- Abstract:
Mechanisms by which the amino acid sequence of polypeptide chains determines their three-dimensional conformation. Topics include: sequence determinants of secondary structure; folding of newly synthesized polypeptide chains within cells; unfolding and refolding of proteins in vitro, folding intermediates aggregation and competing off-pathway reactions; role of chaperonins, isomerases, and other helper proteins; protein recovery problems in the biotechnology industry; diseases associated with protein folding defects.
- Languages:
- English
- Material Type:
- Activities and Labs, Full Course, Homework and Assignments, Lecture Notes, Syllabi
- Media Format:
- Text/HTML, Downloadable docs
- Conditions of Use:
-
Creative Commons Attribution-Noncommercial-Share Alike 3.0
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