Prion Problem Space
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| Type: | Course Related Materials |
| Grade Level: | Post-secondary |
Subject: Science and Technology
Institution Name:
BioQUEST Curriculum Consortium
Collection Name: BioQUEST Curriculum Consortium, BEDROCK Problem Spaces
Abstract:
Prions are relatively small proteins that display dramatically alternate conformations for similar primary structures. Abnormal conformations appear to cause fatal neurological diseases in a wide variety of mammals. Researchers are discovering the mechanisms behind these conformational changes, including differences that may lead to species barriers (or lack thereof) among exposed animals.How do these conformations differ?
How do small sequence differences affect susceptibility to conformational change? This problem space introduces basic skills in protein structure exploration. We will learn to search databases for protein structures, explore the Cn3D software, and propose questions that may be answered with these tools.
Details
Course Type: Learning Module
Material Types: Activities and Labs, Readings, Teaching and Learning Strategies
Media Formats: Text/HTML, Graphics/Photos
Language: English
Conditions of Use: Free to use or adapt with attribution to the authors for any educational purposes only
Additional Information
Geographic
Regional Relevance: All
