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HIV Problem Space

 
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Type: Course Related Materials
Grade Level: Post-secondary
Subject: Science and Technology
Institution Name: BioQUEST Curriculum Consortium

Abstract: In this problem space, you will have access to the following materials: background information on HIV/AIDS, the original Markham et al. reference and other primary literature, viral sequences from each visit of each patient, patients' CD4 counts at each visit, phylogenetic trees of the virus sequences from each patient, a phylogenetic tree of each patient's starting consensus viral sequence, a published activity using this data from the book Microbes Count!, and additional materials prepared by other users of the problem space. You can use this data to explore a number of different questions. Here are a few general questions to get you started: Does the virus evolve the same way in different patients? Are there any specific mutations that cause rapid immune decline? What types of natural selection might be influencing HIV evolution? Is HIV being transmitted between patients after initial infection?

Details

Course Type: Learning Module
Material Types: Activities and Labs, Readings, Teaching and Learning Strategies
Media Formats: Text/HTML, Graphics/Photos
Language: English

Conditions of Use: Free to use or adapt with attribution to the authors for any educational purposes only

Additional Information

Geographic Regional Relevance: All

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