HIV Problem Space

Subject:

Science and Technology

Institution Name:

BEDROCK

Collection:

BioQUEST Curriculum Consortium

Grade Level:

Post-secondary

Abstract:

In this problem space, you will have access to the following materials: background information on HIV/AIDS, the original Markham et al. reference and other primary literature, viral sequences from each visit of each patient, patients' CD4 counts at each visit, phylogenetic trees of the virus sequences from each patient, a phylogenetic tree of each patient's starting consensus viral sequence, a published activity using this data from the book Microbes Count!, and additional materials prepared by other users of the problem space. You can use this data to explore a number of different questions. Here are a few general questions to get you started: Does the virus evolve the same way in different patients? Are there any specific mutations that cause rapid immune decline? What types of natural selection might be influencing HIV evolution? Is HIV being transmitted between patients after initial infection?

Course Type:

Learning Module

Languages:

English

Material Type:

Activities and Labs, Readings, Teaching and Learning Strategies

Media Format:

Graphics/Photos, Text/HTML

Conditions of Use:

Custom Permissions
Teachers, curriculum developers, and students are welcome to download these materials for classroom use. Individual authors hold all rights for any other purposes such as publication or distribution for commercial purposes.