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Keywords: Genomics
(Complete Item Description)
- Abstract: The information presented in each ActionBioscience.org article has been correlated to the U.S. National Science Education Standards (NSES). Articles may be listed below in more than one category of the standards and educators may determine other curricular applications for the articles.
- Subject:
Science and Technology
- Grade Level:
Primary, Secondary
- Collection:
Action Bioscience
(Complete Item Description)
- Abstract: This fun Web site is part of OLogy, where kids can collect virtual trading cards and create projects with them. Here, they see how DNA is used to solve crimes against animals. The activity starts with an introduction to George Amato, an AMNH scientist who sometimes helps the U.S. government solve mysteries. In a three-part online slide show, students see how Amato earned the title "DNA Detective" in 1993 when he helped the U.S. Fish and Wildlife Service catch someone trying to sneak protected reptile skin into the United States. Then students are challenged to Crack the Code, an online game in which they play DNA detective and determine which of a collection of handbags, clothing, figurines, and other items are made from protected species.
(Complete Item Description)
- Abstract: Covers the basics of R software and the key capabilities of the Bioconductor project (a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology and rooted in the open source statistical computing environment R), including importation and preprocessing of high-throughput data from microarrays and other platforms. Also introduces statistical concepts and tools necessary to interpret and critically evaluate the bioinformatics and computational biology literature. Includes an overview of of preprocessing and normalization, statistical inference, multiple comparison corrections, Bayesian Inference in the context of multiple comparisons, clustering, and classification/machine learning.
- Subject:
Science and Technology, Social Sciences, Mathematics and Statistics
- Grade Level:
Post-secondary
- Collection:
JHSPH OpenCourseWare
(Complete Item Description)
- Abstract: The objective of this subject is to teach the design of contemporary information systems for biological and medical data. These data are growing at a prodigious rate, and new information systems are required. This subject will cover examples from biology and medicine to illustrate complete life cycle information systems, beginning with data acquisition, following to data storage and finally to retrieval and analysis. Design of appropriate databases, client-server strategies, data interchange protocols, and computational modeling architectures will be covered. Students are expected to have some familiarity with scientific application software and a basic understanding of at least one contemporary programming language (C, C++, Java, Lisp, Perl, Python, etc.). A major term project is required of all students. Reading is assigned from the contemporary literature, and there is occasional homework.
- Subject:
Science and Technology
- Grade Level:
Post-secondary
- Collection:
MIT OpenCourseWare
(Complete Item Description)
- Abstract: The objective of this subject is to teach the design of contemporary information systems for biological and medical data. These data are growing at a prodigious rate, and new information systems are required. This subject will cover examples from biology and medicine to illustrate complete life cycle information systems, beginning with data acquisition, following to data storage and finally to retrieval and analysis. Design of appropriate databases, client-server strategies, data interchange protocols, and computational modeling architectures will be covered. Students are expected to have some familiarity with scientific application software and a basic understanding of at least one contemporary programming language (C, C++, Java, Lisp, Perl, Python, etc.). A major term project is required of all students. Reading is assigned from the contemporary literature, and there is occasional homework.
- Subject:
Science and Technology
- Grade Level:
Post-secondary
- Collection:
MIT OpenCourseWare
(Complete Item Description)
- Abstract: This course will consider the claim that there is no such thing as race, with a particular emphasis on the question whether races should be thought of as natural kinds: is our concept of race a natural kind concept? Is the term 'race' a natural kind term? If so, is Appiah right to conclude that there are no races? How should one go about "analyzing" the concept of race?
- Subject:
Humanities, Social Sciences
- Grade Level:
Post-secondary
- Collection:
MIT OpenCourseWare
(Complete Item Description)
- Abstract: This course covers the analytical, graphical, and numerical methods supporting the analysis and design of integrated biological systems. Topics include modularity and abstraction in biological systems, mathematical encoding of detailed physical problems, numerical methods for solving the dynamics of continuous and discrete chemical systems, statistics and probability in dynamic systems, applied local and global optimization, simple feedback and control analysis, statistics and probability in pattern recognition.
- Subject:
Science and Technology
- Grade Level:
Post-secondary
- Collection:
MIT OpenCourseWare
(Complete Item Description)
- Abstract: This simple OLogy experiment provides insight into genetics by allowing kids to see and hold real DNA. The activity begins with an explanation about how the Moon, itself, doesn't really change, just our view of it. Then kids go to "See the Moon in Action," an interactive illustration of the Moon's orbit around the Earth, where they can see what the Moon looks like from Earth at eight different positions in its orbit. The activity ends with a Moon Watch Log, a printable PDF file, that kids use to observe the Moon for 28 nights and then compile their illustrations into a flip book.
(Complete Item Description)
- Abstract: This online article, from the museum's Musings newsletter for educators, provides insight into teaching genetics and building genetic literacy. It looks at ways that teachers can: build their own knowledge base stay abreast of the wave of new information about genetics give their students the tools and techniques to make their way in the genomic age.
(Complete Item Description)
- Abstract: In this online article, from the Museum's Musings newsletter for educators, two participants in the Genomics Study Group share their strategies for teaching genetics to high school students. They include tips on: where to begin, including teacher preparation and good content starting points how to use genetics labs when they are available, and alternate approaches when they're not ways to use case studies and topics in the news to increase students' interest guidelines for handling bioethics in the classroom.
(Complete Item Description)
- Abstract: This online article, from the museum's Musings newsletter for educators, looks at the fully functional Genetics Laboratory that was part of the exhibition The Genomic Revolution. It discusses: the significance of the recent sequencing of the human genome in a historical perspective the process visitors underwent during their hour-and-a-half visit to the lab, where they extracted, isolated, visualized, and sequenced their DNA the follow-up activities for visitors on the AMNH Web site.
(Complete Item Description)
- Abstract: This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be?
- Subject:
Science and Technology
- Grade Level:
Post-secondary
- Collection:
MIT OpenCourseWare
(Complete Item Description)
- Abstract: This Web site, created to complement the museum's The Genomic Revolution exhibition, examines the mapping of the genome and its implications.
(Complete Item Description)
- Abstract: General Biochemistry and Molecular Biology - Fall 2007. Molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.
(Complete Item Description)
- Abstract: General Biochemistry and Molecular Biology - Fall 2006. This course covers molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.
(Complete Item Description)
- Abstract: This site gives a detailed overview of the science of genetics, including the Human Genome Project. An introduction helps visitors understand genomes, DNA, genes, chromosomes, and more. Other resources include online audio and video files about genetics and the Human Genome Project, images of genomes, current research news, a glossary, frequently asked questions, and a student page.
(Complete Item Description)
- Abstract: This course will focus on understanding aspects of modern technology displaying exponential growth curves and the impact on global quality of life through a weekly updated class project integrating knowledge and providing practical tools for political and business decision-making concerning new aspects of bioengineering, personalized medicine, genetically modified organisms, and stem cells. Interplays of economic, ethical, ecological, and biophysical modeling will be explored through multi-disciplinary teams of students, and individual brief reports.
- Subject:
Science and Technology
- Grade Level:
Post-secondary
- Collection:
MIT OpenCourseWare
(Complete Item Description)
- Abstract: The OLogy activity takes a look at some of the more amusing traits that are determined by genetics. Students answer four yes/no questions, and then compare their answers with others. The questions are: Do you have a hitchhiker's thumb?Can you curl your tongue? Can you wiggle your ears?Can you raise just one of your eyebrows?
(Complete Item Description)
- Abstract: Hello Dolly is an inquiry oriented activity that places students in the position to ask great questions, develop new relationships, and take a stand on a current hot issue. Issue: Governments around the world are currently debating the potential impact of cloning on society. The purpose of this discussion is to determine how to legislate cloning.
- Subject:
Social Sciences, Science and Technology
- Grade Level:
Secondary
- Collection:
Individual Authors
(Complete Item Description)
- Abstract: This online article is from the Museum's Seminars on Science, a series of distance-learning courses designed to help educators meet the new national science standards. Scenario: Immortality, part of the Genetics, Genomics, Genethics seminar, briefly covers: the age-old quest for eternal life and youth; the recent discovery of telomeres and telomerase; how this discovery could revolutionize the way we treat disease and aging; the ethical and ecological issues that could arise.
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