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(Complete Item Description)
- Abstract:
Unlike most population genetics labs, which involve simulations with beans or beads, this lab provides an opportunity to study a population of living organisms. Using Bar and wild-type Drosophila, students compare allele and genotype frequencies to Hardy-Weinberg expectations. Because the Bar mutation in Drosophila is sex-linked and incompletely dominant, students can determine the exact genotype of a fly from its phenotype. These data are evaluated to determine which (if any) of the five Hardy-Weinberg assumptions have been violated. This real-data approach allows students to appreciate the value of this null model and helps the instructor to discover and correct students' misunderstandings of the model.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
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Association for Biology Laboratory Education (ABLE)
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(Complete Item Description)
- Abstract:
An integrated course stressing the principles of biology. Life processes are examined primarily at the organismal and population levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- SubTopics:
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Animals and Insects
- Collection:
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UMass Boston OpenCourseWare
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- Abstract:
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.014 focuses on the application of these fundamental principles, toward an understanding of microorganisms as geochemical agents responsible for the evolution and renewal of the biosphere and of their role in human health and disease.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- SubTopics:
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Green
- Collection:
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MIT OpenCourseWare
Read the Fine Print
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(Complete Item Description)
- Abstract:
This course presents a unique and challenging perspective on the causes of human disease and mortality. The course focuses on analyses of major causes of mortality in the US since 1900: cancer cardiovascular and cerebrovascular diseases, diabetes, infectious diseases. Students create analytical models to derive estimates for historically variant population risk factors and physiological rate parameters, and conduct analyses of familial data to separately estimate inherited and environmental risks. The course evaluates the basic population genetics of dominant, recessive and non-deleterious inherited risk factors.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
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MIT OpenCourseWare
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(Complete Item Description)
- Abstract:
This course presents a unique and challenging perspective on the causes of human disease and mortality. The course focuses on analyses of major causes of mortality in the US since 1900: cancer cardiovascular and cerebrovascular diseases, diabetes, infectious diseases. Students create analytical models to derive estimates for historically variant population risk factors and physiological rate parameters, and conduct analyses of familial data to separately estimate inherited and environmental risks. The course evaluates the basic population genetics of dominant, recessive and non-deleterious inherited risk factors.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
-
MIT OpenCourseWare
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(Complete Item Description)
- Abstract:
Subject assesses the relationships between sequence, structure, and function in complex biological networks as well as progress in realistic modeling of quantitative, comprehensive functional-genomics analyses. Topics include: algorithmic, statistical, database, and simulation approaches; and practical applications to biotechnology, drug discovery, and genetic engineering. Future opportunities and current limitations critically assessed. Problem sets and project emphasize creative, hands-on analyses using these concepts.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
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MIT OpenCourseWare
Read the Fine Print
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(Complete Item Description)
- Abstract:
This resource provides brief descriptions and a sample exercise for programs contained in BioBytes 3.1, a collection of computer simulation modules. The programs themselves cover a range of topics including ecology, behavioral ecology, physiology, endocrinology, and population genetics.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
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Association for Biology Laboratory Education (ABLE)
