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Impaired axon regeneration in rats after nitrous oxide
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Scientists at the University of Wisconsin have demonstrated that, in male rats, nitrous oxide impairs axon regeneration after multiple types of injuries. Importantly, their results could point toward a possible mechanism. Reporting in the journal Anesthesiology, the authors discuss the effects of nitrous oxide in four model systems: an in vitro evaluation of axon regeneration following a sciatic nerve injury, in vivo tests of regeneration following a sharp spinal cord or an optic nerve injury, and a test of functional recovery after a blunt spinal cord injury. In most experiments, a group of male rats received either a single 70-percent dose of nitrous oxide for two hours, a series of 80-percent doses, or no gas, and were injured or not, in the case of the controls. In some experiments, the rats also received folic acid supplementation, which helps spur axonal recovery. All experiments showed that nitrous oxide reduced the amount of axonal recovery following an injury..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2019
What Kind of Footprint? Carbon Footprint
Read the Fine Print
Educational Use
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Students determine their carbon footprints by answering questions about their everyday lifestyle choices. Then they engineer plans to reduce them. Students learn about their personal impacts on global climate change and how they can help the environment.

Subject:
Applied Science
Engineering
Environmental Science
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kristen Brown
Date Added:
09/18/2014