Keywords: Molecular Biology (160)

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Genetics Book List

Genetics Book List

This OLogy reference list has seven kid-friendly books on genetics. A short ... (more)

This OLogy reference list has seven kid-friendly books on genetics. A short description is given for each title, along with author name and publisher. The list includes: illustrated looks at cells, genes, and DNA, hands-on activities and solve-it-yourself mysteries, and easy-to-understand and thought-provoking explorations of cloning and genetic engineering. (less)

Subject:
Science and Technology
Material Type:
Readings
Collection:
American Museum of Natural History
Provider:
American Museum of Natural History
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A Genetics Lab in a Very Unusual Place

A Genetics Lab in a Very Unusual Place

This online article, from the museum's Musings newsletter for educators, looks at ... (more)

This online article, from the museum's Musings newsletter for educators, looks at the fully functional Genetics Laboratory that was part of the exhibition The Genomic Revolution. It discusses: the significance of the recent sequencing of the human genome in a historical perspective the process visitors underwent during their hour-and-a-half visit to the lab, where they extracted, isolated, visualized, and sequenced their DNA the follow-up activities for visitors on the AMNH Web site. (less)

Subject:
Science and Technology
Material Type:
Teaching and Learning Strategies
Collection:
American Museum of Natural History
Provider:
American Museum of Natural History
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Genomic DNA Isolation From Human Cheek Cells

Genomic DNA Isolation From Human Cheek Cells

In this lab activity students isolate genomic DNA from their cheek cells ... (more)

In this lab activity students isolate genomic DNA from their cheek cells on the inside of their mouths. Students then remove the DNA from those cheek cells. It shows the DNA is in every cell in the body and can be extracted easily. Students use their DNA necklace which they proudly wear around school the rest of the day. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Lesson Plans
Collection:
Pedagogy in Action (SERC)
Provider:
SERC at Carlton College
Author:
Guthmiller, Jim
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Gleevec and the Cell Cycle Problem

Gleevec and the Cell Cycle Problem

Students are given a problem about a relatively new treatment for cancer, ... (more)

Students are given a problem about a relatively new treatment for cancer, Gleevec, and asked to apply and synthesize what they have learned about cell signaling and the eukaryotic cell cycle to explain why this targeted treatment works to prevent cell division with fewer side effects than traditional chemotherapeutic agents. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Collection:
Starting Point (SERC)
Provider:
SERC at Carlton College
Author:
Debby Walser-Kuntz
Sarah Deel
Susan Singer
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Golden Rice: An Intimate Debate Case

Golden Rice: An Intimate Debate Case

In this intimate debate case, students consider whether to support the development ... (more)

In this intimate debate case, students consider whether to support the development and use of Golden Rice as a means to alleviate vitamin A deficiency in the developing world. Since many of the arguments typically raised against genetically modified organisms (GMOs) do not apply to this particular GM crop, students are forced to analyze the facts rather than rely on what they have heard in the media. Developed for an introductory molecular biology undergraduate course, the case could also be used at more senior levels. (less)

Subject:
Science and Technology
Social Sciences
Material Type:
Activities and Labs
Case Study
Lesson Plans
Collection:
Case Study Teaching in Science
Provider:
National Center for Case Study Teaching in Science
Author:
Annie Prud´┐Żhomme Genereux
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How Enzymes Work: Investigating Their Specificity and Susceptibility to Environmental Factors Using Jell-O

How Enzymes Work: Investigating Their Specificity and Susceptibility to Environmental Factors Using Jell-O

This activity is a lab investigation in which students design and conduct ... (more)

This activity is a lab investigation in which students design and conduct experiments using pineapple juice containing the enzyme bromelain and its affect on the substrate gelatin found in Jell-O. The focus of student driven investigations are on enzyme specificity, activity and the impact of environmental factors on enzyme functioning. Based on the original activities from School Improvement in Maryland; "Pineapple/Jell-O Lab," Access Excellence Activities Exchange; "Enzyme Labs Using Jell-O" by Anne McDonald and Michael O'Hare, and AP & Regents Biology; "Lab 8: Pineapple Enzymes and Jell-O Molds" by Kim B. Foglia. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Lesson Plans
Collection:
Pedagogy in Action (SERC)
Provider:
SERC at Carlton College
Author:
Netland, Heather
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Human Chromosome 2

Human Chromosome 2

In this video segment adapted from NOVA: Judgment Day: Intelligent Design on ... (more)

In this video segment adapted from NOVA: Judgment Day: Intelligent Design on Trial, learn how modern genetics and molecular biology offer compelling support for evolution. The video features an interview with biologist Ken Miller. ***Access to Teacher's Domain content now requires free login to PBS Learning Media. (less)

Subject:
Science and Technology
Material Type:
Video Lectures
Collection:
Teachers' Domain
Provider:
PBS Learning Media
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Human DNA Fingerprinting by Polymerase Chain Reaction

Human DNA Fingerprinting by Polymerase Chain Reaction

This experiment uses polymerase chain reaction to demonstrate the polymorphic nature of ... (more)

This experiment uses polymerase chain reaction to demonstrate the polymorphic nature of human DNA. Students obtain samples of their own DNA using a simple mouthwash procedure. PCR is used to amplify a noncoding region of chromosome 1 that contains a repeated DNA sequence. The number of times the sequence repeats can vary from person to person, resulting in a polymorphism. Following amplification, student samples are electrophoresed, stained, and photographed. Each student will see one or two bands in their gel lane, indicating whether they are homozygous or heterozygous for that region of chromosome 1. This experiment is adapted from Advanced DNA Science: An Introduction to Methods of Genome Analysis by Mark V. Bloom, Greg A. Freyer, and David A. Micklos (copyright 1993 Cold Spring Harbor Laboratory and Carolina Biological Supply Company); polymerase chain reaction is covered by patents owned by Hoffman La Roche. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
Cold Spring Harbor Laboratory
Author:
Mark Bloom
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Immunocytochemical Analysis of Sperm Cytoskeleton

Immunocytochemical Analysis of Sperm Cytoskeleton

Monoclonal antitubulin antibodies produced in mice will be used to label bull ... (more)

Monoclonal antitubulin antibodies produced in mice will be used to label bull sperm microtubules and the location of these antibodies will be determined by use of a peroxidase conjugated secondary antibody and the DAB staining reaction. Protocols are presented for use in a second-year student laboratory class given in a multi-section (repeated) format. These protocols include those for preparation of poly-L-lysine coated slides and of bull sperm, as well as those for immunocytochemistry, using the DAB reaction. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
Dalhousie University
Author:
Beth Retallack
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Incorporating Original Genomics Research into Genetics and Molecular Biology Courses

Incorporating Original Genomics Research into Genetics and Molecular Biology Courses

Genomics and bioinformatics have revolutionized biology over the past few years, but ... (more)

Genomics and bioinformatics have revolutionized biology over the past few years, but their impact on education has lagged. A new revolution is possible in the undergraduate curriculum. We have found novel ways to incorporate genomics research into the laboratory components of several courses. In this chapter, we show how we accomplish the typical skill development goals in a genetics or molecular biology course while accomplishing novel research, and provide the protocols for three such research projects that can be modified to suit the course goals or the instructor's research interests. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
Hiram College
Author:
Brad Goodner
Kathy Wheeler
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Intimate Strangers: Unseen Life on Earth

Intimate Strangers: Unseen Life on Earth

This PBS documentary provides an overview of the microbial world and offers ... (more)

This PBS documentary provides an overview of the microbial world and offers an exciting glimpse into the field of microbiology. Meet scientists from around the world investigating the microbial world in diverse locations, from a termite's stomach to a hospital operating room to an African village, and even outer space. These programs - including The Tree of Life, Keepers of the Biosphere, Dangerous Friends and Friendly Enemies, and Creators of the Future - increase the microbial literacy of students, the general public, and biotechnology workers. The site also contains an interactive Game of Life, classroom resources for grades K-12, and information about the companion book published by ASM Press. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Games
Lesson Plans
Collection:
PBS
Provider:
PBS
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Introducing Students to Conservation Genetics Using Sturgeon Caviar and Other Fish Eggs

Introducing Students to Conservation Genetics Using Sturgeon Caviar and Other Fish Eggs

In this laboratory exercise students will learn how to: (a) Isolate DNA ... (more)

In this laboratory exercise students will learn how to: (a) Isolate DNA from individual sturgeon and other fish eggs (available at any local deli that sells caviar) using the DNAzol method, (b) Set up control and species-specific PCR reactions using primers that have been developed for DNA from sturgeon species and (c) Use electrophoresis and methylene blue and/or ethidium bromide staining to visualize the PCR products. This laboratory exercise would allow students to contribute to a growing DNA database on endangered species. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
American Museum of Natural History|St. Francis College|William Paterson University|Yale University
Author:
Claire Leonard
Kathleen A. Nolan
Nancy J. Rosenbaum
Phaedra Doukakis
Rob DeSalle
Tony Catalano
Vadim Birstein
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Introduction to Biology, Fall 2004

Introduction to Biology, Fall 2004

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover ... (more)

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Audio Lectures
Full Course
Homework and Assignments
Syllabi
Video Lectures
Collection:
MIT OpenCourseWare
Provider:
M.I.T.
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An Introduction to DNA: Spectrophotometry, Degradation, and the 'Frankengel' Experiment

An Introduction to DNA: Spectrophotometry, Degradation, and the 'Frankengel' Experiment

In this laboratory students perform three exercises as an introduction to the ... (more)

In this laboratory students perform three exercises as an introduction to the basics of handling and analyzing DNA. In the first, they expose circular plasmid, linear phage, and high molecular weight genomic DNA samples to a variety of physical, thermal, chemical, and enzymatic conditions that might be expected to affect DNA integrity. The DNA's are analyzed by electrophoresis on a group agarose gel. In the second, they pour and reconstruct a "Frankengel" (a gel containing sections with three different agarose concentrations) on which they run a DNA ladder in order to investigate the effect of gel pore size on DNA fragment mobility. In the third, they perform an UV spectrophotometric analysis of DNA from which they learn to make purity and concentration estimates. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Lesson Plans
Collection:
Association for Biology Laboratory Education (ABLE)
Provider:
University of Alberta
Author:
Kimberley Christopher
William Clark
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Introduction to Molecular and Cellular Biology

Introduction to Molecular and Cellular Biology

Though biology as we know it today is a relatively new field, ... (more)

Though biology as we know it today is a relatively new field, we have been studying living things since the beginning of recorded history. This introductory course in biology starts at the microscopic level, with molecules and cells, then moves into the specifics of cell structure and behavior. Upon successful completion of this course, students will be able to: Describe in general terms how life began on Earth; Identify early scientists that played important roles in furthering our understanding of cellular life; Describe the characteristics that define life; List the inorganic and organic molecules that are necessary for life; List the structure and function of organelles in animal and plant cells; List the similarities and differences between animal and plant cells; Describe the reactions in photosynthesis; Explain how the different photosynthetic reactions are found in different parts of the chloroplast; Describe the sequence of photosynthetic reactions; Explain the use of products and the synthesis of reactants in photosynthesis; Explain how protein is synthesized in eukaryotic cells; Describe the similarities and differences between photosynthesis and aerobic respiration; List the reactions in aerobic respiration; Explain the use of products and the synthesis of reactants in aerobic respiration; Describe the similarities and differences between anaerobic and aerobic respiration. (Biology 101; See also: Psychology 203) (less)

Subject:
Science and Technology
Material Type:
Assessments
Audio Lectures
Full Course
Lecture Notes
Readings
Syllabi
Video Lectures
Other
Collection:
Saylor Foundation
Provider:
The Saylor Foundation
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Introduction to Molecular and Cellular Biology - Laboratory

Introduction to Molecular and Cellular Biology - Laboratory

This lab course supplements Introduction to Molecular and Cellular Biology. Although it ... (more)

This lab course supplements Introduction to Molecular and Cellular Biology. Although it does not replicate a true lab experience, it does enable further exploration of some key principles of molecular and cellular biology. In each unit, the student will work through tutorials related to important scientific concepts, and then will be asked to think creatively about how those concepts can be put to practical or experimental use. This lab course also contains activities devoted to learning important techniques in scientific study such as microscope use, DNA extraction, Polymerase Chain Reaction, and examination of DNA microarrays. Upon successful completion of this lab supplement, students will be able to: Identify the important components of scientific experiments and create their own experiments; Identify the molecular differences between proteins, fats, and carbohydrates, and explain the molecular behavior of water; Describe the process of photosynthesis; Describe the process of cellular respiration; Identify the differences between DNA and RNA; Describe the entire transcription/translation process, from gene to protein; Explain how recombinant genomes are formed; Use critical thinking to find ways that any of the above natural processes might be altered or manipulated; Explain how to use a compound light microscope for data collection; Explain how to conduct and use various experimental techniques, including DNA extraction, PCR, and DNA microarrays. (Biology 101 Laboratory) (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Full Course
Homework and Assignments
Readings
Collection:
Saylor Foundation
Provider:
The Saylor Foundation
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Introductory Biology, Spring 2005

Introductory Biology, Spring 2005

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover ... (more)

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.014 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), developmental biology, neurobiology and evolution. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Audio Lectures
Full Course
Homework and Assignments
Syllabi
Collection:
MIT OpenCourseWare
Provider:
M.I.T.
Author:
Gardel, Claudette
Jacks, Tyler
Sive, Hazel
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Introductory Biology, Spring 2005

Introductory Biology, Spring 2005

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover ... (more)

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.014 focuses on the application of these fundamental principles, toward an understanding of microorganisms as geochemical agents responsible for the evolution and renewal of the biosphere and of their role in human health and disease. (less)

Subject:
Science and Technology
Material Type:
Activities and Labs
Assessments
Full Course
Homework and Assignments
Syllabi
Video Lectures
Collection:
MIT OpenCourseWare
Provider:
M.I.T.
Author:
Chisholm, Sallie W.
Mischke, Michelle
Walker, Graham
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Introductory Biology, Spring 2006

Introductory Biology, Spring 2006

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover ... (more)

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.7.014 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), developmental biology, neurobiology and evolution. (less)

Subject:
Science and Technology
Material Type:
Assessments
Audio Lectures
Full Course
Homework and Assignments
Syllabi
Video Lectures
Collection:
MIT OpenCourseWare
Provider:
M.I.T.
Author:
Sive, Hazel
Remix and Share