This case study introduces students to treatment alternatives for depression using a jigsaw method in which groups of students are divided up so that each member of the "home group" becomes the "resident expert" in one of five possible treatment options. Designed for a course in abnormal psychology, this case could be adapted for courses in physiological psychology, pharmacy, and neurobiology.

In this version, developed for classes in cell and molecular biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. This is the Cell & Molecular Biology Edition, which has a different set of questions than the General Biology Edition or the Human Anatomy& Physiology Edition, also in our collection.

In this version, developed for a course in general biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. The General Biology Edition is designed for an introductory biology course. Its basic storyline and core objectives are carried over into a Human Anatomy& Physiology Edition and a Cell& Molecular Biology Edition, also in our collection, each of which has its own set of questions.

In this version, developed for a course in human anatomy and physiology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. This is the Human Anatomy& Physiology Edition, which has a different set of questions than the General Biology Edition or the Cell& Molecular Biology Edition, also in our collection.

This case involves the transfer of a food allergy to a patient who received a combined kidney and liver transplant from a donor who died as the result of an allergic reaction. In addition to learning about the various roles of immune cells, the physiology of anaphylaxis, and the function of antibodies in immune physiology, students explore concepts related to histocompatibilities, organ donation, and organ rejection. The case is appropriate for use in a course in human physiology, a combined course in human anatomy and physiology, or an introductory course in immunology.

In this decision case, students consider the pros and cons of reintroducing grizzly bears into the northwestern United States as they learn about natural resource policy and the wildlife management decision-making process. Students consider four different approaches to grizzly bear recovery and management in the Bitterroot Ecosystem. As part of this, they assume the viewpoint of a stakeholder group, including environmentalists, government officials, residents, hunters, natural resource managers, ranchers, loggers, American Indians, wildlife biologists, and the tourist/recreation industry. The case was developed for use in an upper-division natural resource policy course.

Since caffeine is a widely used substance, especially by college age students, this case on the effects of caffeine on the human body serves as a real-world connection to many students' lives. The case is divided into sections covering background information on caffeine, cell biology and signal transduction, Parkinson's disease, cardiovascular effects, and addiction/withdrawal. The case was designed so that a section can be used alone or in combination with other sections, as dictated by topic/curriculum needs. It would be appropriate for use in a variety of science and health related courses, including anatomy and physiology, disease related courses, genetics, cell biology, molecular biology, biochemistry, and neuroscience.

In this problem-based learning/role playing case, students apply their knowledge of the biology of HIV/AIDS and antiretroviral therapy to developing foreign aid policy for the HIV/AIDS crisis in sub-Saharan Africa. The case was created for a non-majors course in human biology taken mostly by juniors or seniors. It has also been used in a microbiology course for pre-nursing students and in an upper-level microbiology course for biology majors.

In this case study, students role-play members of a task force whose task it is to advise the Director of the National Park Service (their instructor) on the best location for creating a wetland using dredge material from the Potomac River. Students apply previously learned knowledge about wetland ecology (i.e. hydrology, soils, and plants) to a wetland restoration decision. Through the case, students increase their understanding of the principles of ecosystem ecology and the complexity of natural resource management dilemmas. The case was developed for a wetland ecology course, but would also work well in an ecosystem ecology or natural resource management course.

In this case study, students examine data from a number of published studies of the effects of Pacific salmon on freshwater and riparian ecosystems. The case focuses on the interesting phenomenon of spawning salmon acting as nutrient conveyor belts, transporting nutrients from the ocean upstream into freshwater spawning areas and, in some cases, even onto land, reversing the more-typical downstream movement of nutrients. As students work at analyzing and interpreting graphical data, they will also increase their understanding of the principles of biogeochemical cycling and gain an appreciation for the interconnectedness of different types of ecosystems. The topic is appropriate for any course covering ecosystem ecology including, for example, general ecology, freshwater or marine ecology, and environmental science.

This discussion case, in which a university research laboratory is vandalized by environmental activists opposed to genetic engineering, focuses on the science and ethics of genetically modified crops. Students consider both the risks and benefits of biotechnology and explore the positions of various stakeholders, including environmentalists, conservationists, agricultural businesses, research scientists, and farmers. Originally written for a vegetable crops course, the case would be appropriate for a wide variety of courses in which biotechnology is discussed.

Using problem-based learning and role-playing, students analyze the geological origins of the Galapagos Islands, their colonization, species formation, and threats to their biodiversity in this story of a graduate student caught between local fishermen and government officials fighting for control of the islands' natural resources. The case was designed for an introductory biology course where the focus is on evolution. It would also be appropriate for courses in ecology, conservation biology, and natural resources management.

In this dilemma case, the central character, Kathy, must decide whether or not to be tested for known mutations in the breast cancer genes. Students assume the roles of members of Kathy's book club and, using a jigsaw technique, explore the advantages and disadvantages of genetic testing. This case is appropriate for courses that deal with genetics, bioinformatics, biology of cancer, disease prevention, or ethical decision-making.

In 1958, black bass were introduced into Lake Atitlan in the highlands of western Guatemala as a way to attract tourism and boost the local economy, but unforeseen complications resulted in an ecological disaster. Developed for an introductory course in biology, this case study first casts students in the role of the local population at that time and asks them to judge the proposal to introduce the new species of fish. The students then review the ensuing events from a historical perspective based on additional information they receive from the instructor in a progressive disclosure format.

In this interrupted case study, a middle-aged man is having his wisdom teeth surgically removed. He decides to have a general anesthetic, but is unaware of the reaction he will have to halothane. His skeletal muscles go rigid and his body temperature rapidly increases. Students use their knowledge of nerve, synaptic, and muscle function to complete flow diagrams, and consider how each step in the flow diagram could produce maintained muscle contraction. The case is used in a one-semester animal physiology course taken by sophomore and junior science majors. It could also be used in a freshman general biology course or in an anatomy and physiology course.

When a 30-year-old genetic counselor learns that her 38-year-old sister has developed early onset familial Alzheimer's disease (EOFAD), a dominantly inherited disorder that led to their father's death at age 42, she struggles with whether to undergo genetic testing and whether to have children. This interrupted case study examines the impact of genetic testing on people and their families when there is no treatment or cure for a disease. It covers principles of Mendelian inheritance as well as genetic and reproductive technologies ,such as gene tests, pre-implantation genetic diagnosis, and in vitro fertilization. It can be used in introductory biology courses for both majors and non-majors or adapted for more advanced courses in genetics and molecular biology.

Cancer is usually thought to be a disease that affects individuals. But could cancer evolve to become infectious? This case follows the research on a form of transmissible cancer that is decimating the Tasmanian devil, the world's largest carnivorous marsupial. Students analyze two landmark papers that uncovered the molecular mechanism of this cancer, which is known as Tasmanian Devil Facial Tumor Disease (DFTD). Through this case, students develop an understanding of cancer, immunology, microbiology, and cytogenetics in addition to becoming more comfortable using primary research literature. The case was developed for third-year biology students in a molecular biology course, but may also be used in courses in genetics, evolution, immunology, conservation, and research methods.

The characters in this dilemma case, representing the scientific community and government, must make a decision about whether or not to release a virulent pathogen into the environment in order to control the rapidly expanding population of European rabbits in New Zealand. As they work through the case, students grapple with the complex issues associated with introduced species and biological controls. The case was originally written for a wildlife management course taught to college juniors and seniors.

In this true story, students examine the case of a woman with a family predisposition to cancer who is considering genetic testing. Students learn about various aspects of DNA testing and determine how to counsel the woman. The case was designed for an advanced undergraduate molecular biology course but could be modified for an introductory biology, genetics, or ethics classes.