Methods in Biostatistics I

Abstract:: Presents fundamental concepts in applied probability, exploratory data analysis, and statistical inference, focusing on probability and analysis of one and two samples. Topics include discrete and continuous probability models; expectation and variance; central limit theorem; inference, including hypothesis testing and confidence for means, proportions, and counts; maximum likelihood estimation; sample size determinations; elementary non-parametric methods; graphical displays; and data transformations.

Subject:: Mathematics and Statistics, Science and Technology, Social Sciences
Grade Level:: Post-secondary
Collection:: JHSPH OpenCourseWare

Methods in Biostatistics II

Abstract:: Presents fundamental concepts in applied probability, exploratory data analysis, and statistical inference, focusing on probability and analysis of one and two samples. Topics include discrete and continuous probability models; expectation and variance; central limit theorem; inference, including hypothesis testing and confidence for means, proportions, and counts; maximum likelihood estimation; sample size determinations; elementary non-parametric methods; graphical displays; and data transformations.

Abstract:: The activity begins with an explanation of the Caesar Shift for message encryption (Singh, 1999). The Caesar Shift is a translation of the alphabet; for example, a five-letter shift would code the letter a as f, b as g, … z as e. We describe a five-step process for decoding an encrypted message. First, groups of size 4 construct a frequency table of the letters in two lines of a coded message. Second, students construct a bar chart for a reference message of the frequency of letters in the English language. Third, students create a bar chart of the coded message. Fourth, students visually compare the bar chart of the reference message (step 2) to the bar chart of the coded message (step 3). Based on this comparison, students hypothesize a shift. Fifth, students apply the shift to the coded message.

Abstract:: This activity provides students with 24 histograms representing distributions with differing shapes and characteristics. By sorting the histograms into piles that seem to go together, and by describing those piles, students develop awareness of the different versions of particular shapes (e.g., different types of skewed distributions, or different types of normal distributions), that not all histograms are easy to classify, that there is a difference between models (normal, uniform) and characteristics (skewness, symmetry, etc.).

Abstract:: This activity is an advanced version of the “Keep your eyes on the ball” activity by Bereska, et al. (1999). Students should gain experience with differentiating between independent and dependent variables, using linear regression to describe the relationship between these variables, and drawing inference about the parameters of the population regression line. Each group of students collects data on the rebound heights of a ball dropped multiple times from each of several different heights. By plotting the data, students quickly recognize the linear relationship. After obtaining the least squares estimate of the population regression line, students can set confidence intervals or test hypotheses on the parameters. Predictions of rebound length can be made for new values of the drop height as well. Data from different groups can be used to test for equality of the intercepts and slopes. By focusing on a particular drop height and multiple types of balls, one can also introduce the concept of analysis of variance.