Explores the changing roles, ethical conflicts, and public perceptions of science and scientists in American society from World War II to the present. Studies specific historical episodes focusing on debates between scientists and the contextual factors influencing their opinions and decisions. Topics include the atomic bomb project, environmental controversies, the Challenger disaster, biomedical research, genetic engineering, (mis)use of human subjects, scientific misconduct and whistleblowing.
Many difficult ethical questions have arisen from the explosive growth of biomedical research and the health-care industry since World War II. When and how should doctors be allowed to help patients end their lives? Should embryos be cloned for research and/or reproduction? Should parents be given control over the genetic make-up of their children? What sorts of living things is it appropriate to use as research subjects? How should we distribute scarce and expensive medical resources? While some of these questions are genuinely new, products of rapid changes in biomedical technology, others have been debated for centuries. Drawing on philosophy, history, and anthropology, this course will show students how problems in bioethics can be approached from a variety of perspectives, with the aim of understanding how we have gotten where we are, and how we should decide where to go next.
" This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) — what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers."
The purpose of this activity is to introduce students to the concept of the engineering design process and to teach them how to apply it. In "Broken Bones," students will explore the steps of the engineering design process. They will first receive some background instruction about biomedical engineering or bioengineering. Then they will learn about material selection and material properties by using a guide created for them. Students will then break into small groups and brainstorm. Each student group is assigned a specific design problem. Students will be given materials and asked to create a prototype. To finish, students will communicate their solution through a poster presentation.
Subject:
Mathematics and Statistics, Science and Technology
Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.
" This is an advanced course on modeling, design, integration and best practices for use of machine elements such as bearings, springs, gears, cams and mechanisms. Modeling and analysis of these elements is based upon extensive application of physics, mathematics and core mechanical engineering principles (solid mechanics, fluid mechanics, manufacturing, estimation, computer simulation, etc.). These principles are reinforced via (1) hands-on laboratory experiences wherein students conduct experiments and disassemble machines and (2) a substantial design project wherein students model, design, fabricate and characterize a mechanical system that is relevant to a real world application. Students master the materials via problems sets that are directly related to, and coordinated with, the deliverables of their project. Student assessment is based upon mastery of the course materials and the student's ability to synthesize, model and fabricate a mechanical device subject to engineering constraints (e.g. cost and time/schedule)."
The course covers basic concepts of biomedical engineering and their connection with the spectrum of human activity. It serves as an introduction to the fundamental science and engineering on which biomedical engineering is based. Case studies of drugs and medical products illustrate the product development-product testing cycle, patent protection, and FDA approval. It is designed for science and non-science majors.
This online article is from the Museum's Seminars on Science, a series of distance-learning courses designed to help educators meet the new national science standards. Genetically Modified Food: Golden Rice, part of the Genetics, Genomics, Genethics seminar, briefly covers: why more than a million people in developing countries are struck with irreversible blindness; the proposed solution of genetically engineering rice to contain carotenoid, the precursor of Vitamin A; environmental concerns about golden rice's threats to biodiversity and other suggested solutions.
This OLogy reference list has seven kid-friendly books on genetics. A short description is given for each title, along with author name and publisher. The list includes: illustrated looks at cells, genes, and DNA, hands-on activities and solve-it-yourself mysteries, and easy-to-understand and thought-provoking explorations of cloning and genetic engineering.
Subject assesses the relationships between sequence, structure, and function in complex biological networks as well as progress in realistic modeling of quantitative, comprehensive functional-genomics analyses. Topics include: algorithmic, statistical, database, and simulation approaches; and practical applications to biotechnology, drug discovery, and genetic engineering. Future opportunities and current limitations critically assessed. Problem sets and project emphasize creative, hands-on analyses using these concepts. From the course home page: In addition to the regular lecture sessions, supplementary sections are scheduled to address issues related to Perl, Mathematica and biology.
The Genetics Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.
This fun Web site is part of OLogy, where kids can collect virtual trading cards and create projects with them. Here, they take a look at some of the questions that go hand-in-hand with genetic cloning technologies. The site opens by telling kids that in the future, technologies like cloning may be very common and that some of the decisions we will need to make in coming years are hard. Then, they are asked to imagine that it is the year 2020 and to take a peek at what's on the minds of one future family. Using this family's thoughts as a base, kids are asked hard questions such as, "Do people have the right to know the chicken they're eating is from a clone?" and "Is it okay for parents to clone their favorite child?"
" This class is a project-based introduction to the engineering of synthetic biological systems. Throughout the term, students develop projects that are responsive to real-world problems of their choosing, and whose solutions depend on biological technologies. Lectures, discussions, and studio exercises will introduce (1) components and control of prokaryotic and eukaryotic behavior, (2) DNA synthesis, standards, and abstraction in biological engineering, and (3) issues of human practice, including biological safety; security; ownership, sharing, and innovation; and ethics. Enrollment preference is given to freshmen. This subject was originally developed and first taught in Spring 2008 by Drew Endy and Natalie Kuldell. Many of Drew's materials are used in this Spring 2009 version, and are included with his permission. This OCW Web site is based on the OpenWetWare class Wiki, found at OpenWetWare: 20.020 (S09)"
This fun Web site is part of OLogy, where kids can collect virtual trading cards and create projects with them. Here, they learn about the many ecosystems in the ocean. The site opens by telling kids that people have learned to change the food we eat. The first comic strip looks at a farmer who works to produce a larger, redder, tastier tomato. The second comic strip tells kids about genetic modification and imagines a scientist putting the flounder's "anti-freeze" gene inside the DNA of a tomato. Food for Thought presents kids with two scenarios about genetically modified food, asking them if they think they're good ideas.
This course examines one of the most enduring and influential forms of identity and experience in the Americas and Europe, and in particular the ways race and racism have been created, justified, or contested in scientific practice and discourse. Drawing on classical and contemporary readings from Du Bois to Gould to Gilroy, we ask whether the logic of race might be changing in the world of genomics and informatics, and with that changed logic, how we can respond today to new configurations of race, science, technology, and inequality. Considered are the rise of evolutionary racism; debates about eugenics in the early twentieth century; Nazi notions of "racial hygiene"; nation-building projects and race in Latin America; and the movement in modern biology from race to populations to genes and genomes.
In this online article, from the museum's Musings newsletter for educators, the Youth and Family Programs Director offers advice on how to integrate genetics learning into students' daily lives. The tips she gives are: make it simple find local or online resources check out the news use an interdisciplinary approach to ethical issues expose students to new career options remember that the best science generates more questions.
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