(Complete Item Description)
- Abstract:
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The homeobox genes that define the basic body plan of mice and fruit flies are illustrated in this graphic from The Human Evolution Coloring Book by Adrienne Zihlman. The accompanying article describes how these genes act as molecular architects in all animal species.
- Subject:
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Science and Technology
- Grade Level:
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Secondary
- SubTopics:
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Animals and Insects
- Collection:
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Teachers' Domain
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- Abstract:
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This laboratory investigates one form of genetic recombination in bacteria. This process, called conjugation, occurs when one bacteria transfers DNA to another bacteria. Two different strains of Escherichia coli are used: an Hfr strain with the F factor integrated into the bacterial chromosome acting as the donor, and an F-strain lacking the fertility factor acting as a recipient. The F-strain is auxotrophic for certain genetic markers and the ordered transfer of markers from the Hfr strain to the F-strain is used to map gene locations on the bacterial chromosome.
- Subject:
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Science and Technology
- Grade Level:
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Post-secondary
- Collection:
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Association for Biology Laboratory Education (ABLE)
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- Abstract:
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This interactive feature provides a microscopic view of the 24 Human chromosomes. Each chromosome is labeled with the names of some of the genetic conditions and traits associated with particular regions on that chromosome.
- Subject:
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Science and Technology
- Grade Level:
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Secondary
- Collection:
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Teachers' Domain
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Read the Fine Print
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- Abstract:
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.
- Subject:
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Mathematics and Statistics,
Science and Technology
- Grade Level:
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Primary,
Secondary
- Collection:
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TeachEngineering
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- Abstract:
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In this article, Dr. Eric Lander of the Human Genome Project comments on the use of DNA as an identification tool -- the theoretical versus the practical results.
- Subject:
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Science and Technology
- Grade Level:
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Primary,
Secondary
- Collection:
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Teachers' Domain
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Read the Fine Print
Rate this resource by using the left and right arrow keys and pressing Enter.
Read the Fine Print
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Read the Fine Print
(Complete Item Description)
- Abstract:
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Genetics is the branch of biology that studies the means by which traits are passed on from one generation to the next and the causes of similarities and differences between related individuals. In this course, the student will take a close look at chromosomes, DNA, and genes. The student will learn how hereditary information is transferred, how it can change, how it can lead to human disease and be tested to indicate disease, and much more. Upon successful completion of this course, students will be able to: give a brief synopsis of the history of genetics by explaining the fundamental genetic concepts covered in this course as they were discovered through time; identify the links between Mendel's discoveries (often represented by Punnett squares) with mitosis and meiosis, dominance, penetrance, and linkage; recognize the role of simple probability in genetic inheritance; apply advanced genetic concepts, including genetic mapping and transposons, to practical applications, including pedigree analysis and corn kernel color; identify the cause behind several genetic diseases currently prevalent in society (such as color blindness and hemophilia) and recognize the importance of genetic illness throughout history; compare and contrast advanced concepts of chromosomal, bacterial, human, and population genetics; recognize the similarities and differences between nuclear, chloroplast, and mitochondrial DNA; describe the fundamentals of population genetics, calculate gene frequencies in a give scenario, predict future gene frequencies over future generations, and define the role of evolution in gene frequency shift over time; recall, analyze, synthesize, and build on the foundational material to then learn the cutting-edge technological advances in genetics, including genomics, population and evolutionary genetics, and QTL mapping. (Biology 305)
- Subject:
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Science and Technology
- Grade Level:
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Post-secondary
- Collection:
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Saylor Foundation
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- Abstract:
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In this article by An Meeker-O'Connell, discover how DNA evidence is processed before it goes to court.
- Subject:
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Science and Technology
- Grade Level:
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Primary,
Secondary
- Collection:
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Teachers' Domain
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From something as small and complex as a chromosome to something as seemingly simple as the weather, sex determination systems vary significantly across the animal kingdom. Biologist and teacher Aaron Reedy shows us the amazing differences between species when it comes to determination of gender. A quiz, thought provoking question, and links for further study are provided to create a lesson around the 6-minute video. Educators may use the platform to easily "Flip" or create their own lesson for use with their students of any age or level.
- Subject:
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Science and Technology
- Grade Level:
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Secondary,
Post-secondary
- Collection:
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TED-Ed
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- Abstract:
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This 2-hour laboratory exercise isolates chromosomes from bone marrow. After the chromosomes are isolated, they are stained and chromosomal spreads are examined microscopically to establish diploid number and chromosome morphology. This technique is applicable to all small mammals.
- Subject:
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Science and Technology
- Grade Level:
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Post-secondary
- Collection:
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Association for Biology Laboratory Education (ABLE)
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This exercise provides a hands on introduction to the preparation of human karyotypes. Students practice karyotype preparation using Biophotos of normal male and female chromosome smears. The students then prepare a karyotype using a Biophoto of chromosomes from a Down syndrome individual or from a Down syndrome carrier.
- Subject:
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Science and Technology
- Grade Level:
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Post-secondary
- Collection:
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Association for Biology Laboratory Education (ABLE)
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- Abstract:
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Students use DNA profiling to determine who robbed a bank. After they learn how the FBI's Combined DNA Index System (CODIS) is used to match crime scene DNA with tissue sample DNA, students use CODIS principles and sample DNA fragments to determine which of three suspects matches evidence obtain at a crime location. They communicate their results as if they were biomedical engineers reporting to a police crime scene investigation.
- Subject:
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Mathematics and Statistics,
Science and Technology
- Grade Level:
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Secondary
- Collection:
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TeachEngineering
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