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(Complete Item Description)
- Abstract:
Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
-
MIT OpenCourseWare
Remix and Share
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(Complete Item Description)
- Abstract:
" This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants."
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
-
MIT OpenCourseWare
Read the Fine Print
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(Complete Item Description)
- Abstract:
In this activity, students use wood, wax paper and oil to investigate the importance of lubrication between materials and to understand the concept of friction. Using wax paper and oil placed between pieces of wood, the function of lubricants between materials is illustrated. Students extend their understanding of friction to bones and joints in the skeletal system and become aware of what engineers can do to help reduce friction in the human body as well as in machines.
- Subject:
- Mathematics and Statistics, Science and Technology
- Grade Level:
- Primary
- Collection:
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TeachEngineering
Read the Fine Print
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(Complete Item Description)
- Abstract:
This patient education program explains osteoarthritis and how it affects the joints. Causes, symptoms, risk factors, diagnosis, and treatment options are also reviewed. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
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H.E.A.L.
Read the Fine Print
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(Complete Item Description)
- Abstract:
This patient education program explains osteoarthritis and how it affects the joints. Causes, symptoms, risk factors, diagnosis, and treatment options are also reviewed. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
-
H.E.A.L.
Read the Fine Print
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(Complete Item Description)
- Abstract:
This lesson goes over the parts of the human respiratory system and the gas exchange process that occurs in the lungs. It also covers changes in the respiratory system that occur during spaceflight, such as decreased lung capacity.
- Subject:
- Mathematics and Statistics, Science and Technology
- Grade Level:
- Primary
- Collection:
-
TeachEngineering
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(Complete Item Description)
- Abstract:
The principles and practice of tissue engineering (and regenerative medicine) are taught by faculty of the Harvard-MIT Division of Health Sciences and Technology (HST) and Tsinghua University, Beijing, China. The principles underlying strategies for employing selected cells, biomaterial scaffolds, soluble regulators or their genes, and mechanical loading and culture conditions, for the regeneration of tissues and organs in vitro and in vivo are addressed. Differentiated cell types and stem cells are compared and contrasted for this application, as are natural and synthetic scaffolds. Methodology for the preparation of cells and scaffolds in practice is described. The rationale for employing selected growth factors is covered and the techniques for incorporating their genes into the scaffolds are examined. Discussion also addresses the influence of environmental factors including mechanical loading and culture conditions (e.g., static versus dynamic). Methods for fabricating tissue-engineered products and devices for implantation are taught. Examples of tissue engineering-based procedures currently employed clinically are analyzed as case studies.
- Subject:
- Science and Technology
- Grade Level:
- Post-secondary
- Collection:
-
MIT OpenCourseWare
