This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Traumatic brain injury (TBI), or brain damage caused by a sudden blow or jolt to the head, is a leading cause of death and disability worldwide. The mechanisms are complex and differ among patients, making TBI difficult to treat, and anti-inflammatory agents that are effective in animal models have been less promising in human trials, indicating that better treatments are needed. To explore new strategies, a recent study investigated the effect of the anti-inflammatory compound ACT001 on TBI. In mice, ACT001 reduced brain damage and improved motor function after TBI by reducing trauma-induced activation of microglia, which are immune cells of the central nervous system. In vitro, ACT001 also reduced activation of mouse and rat microglia induced by the bacterial toxin lipopolysaccharide (LPS) and downregulated LPS-induced secretion of proinflammatory molecules in a mouse microglial cell line..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This patient education program explains cerebral palsy (CP), the causes and risk …
This patient education program explains cerebral palsy (CP), the causes and risk factors, symptoms and complications, diagnosis, prevention, and treatment options. It also reviews brain anatomy, particularly that of the motor skills areas. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.
Brain development can be damaged by environmental chemicals. Philippe Grandjean, University of …
Brain development can be damaged by environmental chemicals. Philippe Grandjean, University of Southern Denmark and Harvard School of Public Health, explains the erroneous assumptions made over time about this. Studies from Faroe Islands, where people have been exposed to toxic agents, shows how this affects brains of children and their IQ levels.
A presentation with Professor Philippe Grandjean about the dangers of chemical interference …
A presentation with Professor Philippe Grandjean about the dangers of chemical interference with the developing brain. This presentation, “Children’s health - Risks to brain development from exposure to environmental chemicals”, presented on 6th November, 2019, meeting of the French High Council for Public Health (Haut Conseil de la Santé Publique, HCSP), at the Ministry for Solidarity and Health in Paris.
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