Subject assesses the relationships between sequence, structure, and function in complex biological networks as well as progress in realistic modeling of quantitative, comprehensive functional-genomics analyses. Topics include: algorithmic, statistical, database, and simulation approaches; and practical applications to biotechnology, drug discovery, and genetic engineering. Future opportunities and current limitations critically assessed. Problem sets and project emphasize creative, hands-on analyses using these concepts.
In this seminar, we will discuss some of the main themes that have arisen in the field of systems biology, including the concepts of robustness, stochastic cell-to-cell variability, and the evolution of molecular interactions within complex networks.
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