This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women and is characterized by irregular periods, infertility, and hirsutism. Patients with PCOS also regularly experience gut dysbiosis, but the specific role of dysbiosis in the pathology of PCOS is not clear. To investigate this, researchers administered two different treatments to rats – the androgen dehydroepiandrosterone (DHEA) to induce PCOS-like symptoms and antibiotics to deplete the existing microbiota and thereby produce “pseudo germ-free” rats. In the androgen-treated rats, depletion of the microbiota did not protect them from PCOS-like symptoms, but transplanting microbiota from androgen-treated rats into pseudo germ-free rats triggered disruption of reproductive hormone balance and altered liver metabolism..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Biology
- Life Science
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 10/16/2021