Biochemistry is the study of the chemical processes and compounds, such as cellular makeup, that bring about life in organisms. This course will look at how these formed biomolecules interact and produce many of life's necessary processes. Also it will look at the most commonly used techniques in biochemistry research. Upon successful completion of this course, students will be able to: recognize and describe the structure of the following basic biomolecules: nucleic acids, amino acids, lipids, carbohydrates; diagram how these basic biomolecules are used as building blocks for more complex biomolecules; differentiate between reactions that create biomolecules; describe how these biomolecules are used in specific cellular pathways and processes; analyze how feedback from one pathway influences other pathways; explain how energy is utilized by a cell; indicate how biomolecules and pathways are regulated; describe how enzymes play a key role in catalysis; assess which biochemical technique should be used to study a given biochemical problem. (Biology 401; See also: Chemistry 109)

This HIBB presentation provides background information on bases, amino acids, proteins, nucleotides and DNA. The presentation then explains what bioinformatics is, lists some examples, and demonstrates some tools. It demonstrates tools which compare parts of human and chimp genes, and illustrate drug resistance analysis and HIV subtype analysis. It then discusses some ethical and clinical aspects to bioinformatics.

This HIBB presentation provides background information on bases, amino acids, proteins, nucleotides and DNA. The presentation then explains what bioinformatics is, lists some examples, and demonstrates some tools. It demonstrates tools which compare parts of human and chimp genes, and illustrate drug resistance analysis and HIV subtype analysis. It then discusses some ethical and clinical aspects to bioinformatics.

This HIBB presentation provides background information on bases, amino acids, proteins, nucleotides and DNA. The presentation then explains what bioinformatics is, lists some examples, and demonstrates some tools. It demonstrates tools which compare parts of human and chimp genes, and illustrate drug resistance analysis and HIV subtype analysis. It then discusses some ethical and clinical aspects to bioinformatics.

This HIBB presentation provides background information on bases, amino acids, proteins, nucleotides and DNA. The presentation then explains what bioinformatics is, lists some examples, and demonstrates some tools. It demonstrates tools which compare parts of human and chimp genes, and illustrate drug resistance analysis and HIV subtype analysis. It then discusses some ethical and clinical aspects to bioinformatics.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.014 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), developmental biology, neurobiology and evolution.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.014 focuses on the application of these fundamental principles, toward an understanding of microorganisms as geochemical agents responsible for the evolution and renewal of the biosphere and of their role in human health and disease.

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.7.014 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), developmental biology, neurobiology and evolution.

This course is a continuation of Organic Chemistry I. The student will focus on four most important classes of reactions: electrophilic substitution at aromatic rings, nucleophilic addition at carbonyl compounds, hydrolysis of carboxylic acids, and carbon-carbon bond formation using enolates. The enolate portion of this course will cover the reactivity of functional groups. The student will also look at synthetic strategies for making simple, small organic molecules, using the knowledge of organic chemistry accumulated thus far. This course also introduces biological molecules, including carbohydrates, peptides and proteins, lipids, and nucleic acids, from a molecular perspective. The student will learn how chemical reactions, especially oxidation and reduction reactions, form the basis of all life. Note that in biology, the student would study the functionality of these structures by asking, 'How do they operate?' whereas in the field of organic chemistry, the student will ask: 'What are they made of?' The student will conclude this course with a unit on spectroscopy. Upon successful completion of this course, the student will be able to: Identify the chemistry and basic mechanisms of the following functional groups: ethers, epoxides, thiols, sulfides, benzene, amines, aldehydes, ketones, and carboxylic acids and their derivatives; Plan the synthesis of unsymmetrical ethers, amines, and carboxylic acid derivatives (esters, amides, etc.); Predict the product(s) of an electrophilic addition reaction involving conjugated dienes; Use the Diels-Alder reaction on conjugated dienes to form new carbon-carbon bonds and chiral centers of a desired configuration (R or S); Determine whether a molecule is aromatic, non-aromatic, or anti-aromatic; Indicate the position in which an electrophile will be added on an aromatic ring, given the other substituents present; Identify the products and mechanisms of electrophilic and nucleophilic aromatic substitution reactions; Demonstrate mastery of enolate chemistry and techniques for C-C bond formation; Plan the synthesis of simple molecules using the reactions learned throughout both the Organic Chemistry I and Organic Chemistry II courses; Describe the chemistry associated with biological molecules such as amino acids, nucleic acids, lipids, and carbohydrates; Identify different monosaccharides, disaccharides, aldoses, and ketoses, as well as reducing and non-reducing carbohydrates; Identify the twenty naturally occurring amino acids and describe the mechanisms associated with peptide cleavage and synthesis; Use spectroscopy (mass spectrometry, UV-Vis spectrometry, infrared spectrometry, and nuclear magnetic resonance) to characterize an organic molecule. (Chemistry 104; See also: Biology 108)

To introduce students to basic techniques of plant tissue culture and determine the effects of amino acids on growth of carrot or corn plant callus.

Mechanisms by which the amino acid sequence of polypeptide chains determines their three-dimensional conformation. Topics include: sequence determinants of secondary structure; folding of newly synthesized polypeptide chains within cells; unfolding and refolding of proteins in vitro, folding intermediates aggregation and competing off-pathway reactions; role of chaperonins, isomerases, and other helper proteins; protein recovery problems in the biotechnology industry; diseases associated with protein folding defects.

NBC's Lester Holt looks at the physically demanding pre-season ritual of NFL training camp. Douglas Casa, head of the Korey Stringer Institute at the University of Connecticut, and athletic trainers from the Pittsburgh Steelers explain what NFL players must do to stay hydrated and replenish the essential nutrients needed to maintain good health during rigorous practices. "Science of NFL Football" is a 10-part video series funded by the National Science Foundation and produced in partnership with the National Football League.