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Antibiotics make way for fungal invasion in human gut
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Antibiotics are powerful for fighting infection. But they could create a dangerous imbalance in the gut, where the eradication of harmful bacteria might make room for gut fungi to invade. To find out, researchers analyzed stool samples from 14 healthy participants. Samples were collected over 3 months following a 6-day course of antibiotics. While the bacterial community mostly rebounded over those 3 months, the fungal community shifted from one characterized largely by mutually beneficial interactions (red) to one fraught with competitive interactions (blue) with half of the bacterial-fungal interactions detected before the antibiotic treatment disappearing 3 months later. Metagenomics data revealed that certain bacteria normally help keep opportunistic fungal pathogens like Candida albicans in check. Understanding how could help researchers find ways to restore balance to the gut microbiome following drug treatment or during disease..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2020
Identifying Biases and their Potential Solutions in Human Microbiome Studies
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Recent advances in DNA sequencing technology have made it possible to investigate community-wide changes in microbes that live on and within the human body. Unfortunately, different studies can have different results, often due to systemic biases introduced at various stages of sequence-based microbiome studies. Sample collection can introduce biases depending on the source site and method of collection. Consistent collection methods are essential, and care must be taken when choosing storage methods, times, and reagents. Increasing the usage of benchmark samples and technical replicates may also help to mitigate batch effects during sample collection and processing. Additional bias can arise during DNA extraction due to differing extraction efficiencies, contamination, and the introduction of DNA from non-living organisms. Introducing steps to this process to reduce contamination and measure inter-plate and inter-assay variability will help to reduce these effects..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/14/2021
Isotopes and Atomic Mass
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CC BY
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Are all atoms of an element the same? How can you tell one isotope from another? Use the sim to learn about isotopes and how abundance relates to the average atomic mass of an element.

Subject:
Chemistry
Physical Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Emily Moore
John Blanco
Kathy Perkins
Kelly Lancaster
Robert Parson
Sam Reid
Trish Loeblein
Date Added:
07/18/2011
Isotopes and Atomic Mass (AR)
Unrestricted Use
CC BY
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Are all atoms of an element the same? How can you tell one isotope from another? Use the sim to learn about isotopes and how abundance relates to the average atomic mass of an element.

Subject:
Chemistry
Physical Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Emily Moore
John Blanco
Kathy Perkins
Kelly Lancaster
Patricia Loblein
Robert Parson
Sam Reid
Date Added:
05/13/2011
Microbiota therapeutic RBX2660 shows promising results in patients with recurrent Clostridioides difficile infection
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Fecal microbiota transplantation is a promising procedure for preventing recurrent Clostridioides difficile infection (rCDI), which is the most frequently identified healthcare-associated infection in the US. Unfortunately, the effects of microbiota transplantations on the microbiome and resistome of rCDI patients have not been examined in detail. To address that gap, researchers recently conducted a randomized, double-blind, placebo-controlled clinical trial of the investigational microbiota therapeutic RBX2660 for patients with rCDI. Over the first 7 days after treatment, all patients showed significant recovery of gut microbiome architecture and a decreased abundance of antibiotic-resistance genes. However, patients receiving RBX2660 showed more significant and longer-lasting microbiome and resistome shifts toward a balanced configuration than those receiving the placebo..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2020
New survey explores hidden mega-colonies of Adélie penguins in Antarctica
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Recognized by the distinctive white ring around its eyes, the Adélie penguin is only one of two species of penguin whose only home is Antarctica. While Adélie numbers have been observed to decline in some regions amid a changing climate, the truth is surprisingly little is known about the penguins’ actual distribution along Antarctica’s coastline. A 2015 land-and-air survey explored previously unreported colonies of Adélie here, in a cluster of ice-choked islands called the Danger Islands. The discovery could mark an important technological turning point in species tracking that would have clear implications for preserving biodiversity. Researchers conducted their survey from aboard a research vessel and on the grounds of several of the Danger Islands—only one of which had ever been inspected for Adélie penguins. They counted nests [manually], [from panoramic photos], and [from imagery captured by drones]. In all, the team tallied 751,527 pairs of Adélie penguins in the Danger Islands..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Ecology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/13/2019
New survey explores hidden mega-colonies of Adélie penguins in Antarctica
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Recognized by the distinctive white ring around its eyes, the Adélie penguin is only one of two species of penguin whose only home is Antarctica. While Adélie numbers have been observed to decline in some regions amid a changing climate, the truth is surprisingly little is known about the penguins’ actual distribution along Antarctica’s coastline. A 2015 land-and-air survey explored previously unreported colonies of Adélie here, in a cluster of ice-choked islands called the Danger Islands. The discovery could mark an important technological turning point in species tracking that would have clear implications for preserving biodiversity. Researchers conducted their survey from aboard a research vessel and on the grounds of several of the Danger Islands—only one of which had ever been inspected for Adélie penguins. They counted nests [manually], [from panoramic photos], and [from imagery captured by drones]. In all, the team tallied 751,527 pairs of Adélie penguins in the Danger Islands..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Ecology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/13/2019
Understanding the dietary needs of the red mason bee
Unrestricted Use
CC BY
Rating
0.0 stars

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Plant diversity is quickly dwindling across the world. That’s put our planet’s pollinators in danger. Pollen contains a variety of nutritional elements that are key to life itself. Not only are global changes affecting pollen amounts, they’re also affecting pollen varieties. This means that many pollinators, including bees, aren’t eating the best-balanced diet they need to survive. Understanding how the elemental ingredients in pollen affect different traits in bees, such as their survival, body mass, and ability to protect themselves, could help scientists determine whether and how the scarcity of specific nutrients affects them. And it could lead to new ways of conserving pollinators and the critical roles they play in many ecosystems. For their part, researchers from Jagiellonian University in Poland examined the effects of an inadequate supply of potassium, sodium, and zinc in pollen on _Osmia bicornis_, the red mason bee..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
10/13/2021